Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.37 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.36 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20662073 | 0.90 | CHRM4 (0.44) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL22877861 | 0.84 | CXCR4 (0.43) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL18879327 | 0.82 | GNAO1 (0.41) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL18408989 | 0.82 | SMN1; SMN2 (0.44) | CHRM2CHRM1SIGMAR1USP2ALDH1A1 | |
| SCHEMBL19569948 | 0.81 | CHRM2 (0.42) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL19200868 | 0.80 | RAB9A (0.37) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL18737015 | 0.79 | CHRM4 (0.44) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL18799740 | 0.78 | RAB9A (0.38) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL18852718 | 0.78 | GNAI3 (0.36) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL23542114 | 0.77 | ALDH1A1 (0.43) | CHRM2CHRM1SIGMAR1USP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10576453-B2 | Membrane fabrication methods using organosilica materials and uses thereof | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2020-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10576453-B2 | Membrane fabrication methods using organosilica materials and uses thereof | ZYX, GPX4, PLA2G2A | CHRM2 2052/4885CHRM4 481/4885CHRM5 1901/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.