Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 11/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 10/20 | 0.33 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.33 |
| ▸ | QRFPR | Q96P65 | 1/20 | 0.33 |
| ▸ | SIRT5 | Q9NXA8 | 3/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.32 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21782007 | 0.80 | C3AR1 (0.37) | SIRT2SIRT1QRFPRSIRT5 | |
| SCHEMBL21781923 | 0.77 | QRFPR (0.42) | QRFPR | |
| SCHEMBL20729911 | 0.75 | LMNA (0.36) | SIRT2SIRT1SIRT5SIRT3 | |
| SCHEMBL21782008 | 0.75 | CHRNB2 (0.44) | SIRT2SIRT1 | |
| SCHEMBL18822697 | 0.70 | SIRT2 (0.34) | SIRT2SIRT1SIRT5SIRT3 | |
| SCHEMBL21649652 | 0.69 | SIRT1 (0.42) | SIRT2SIRT1 | |
| SCHEMBL22561449 | 0.68 | C3AR1 (0.43) | SIRT2SIRT1QRFPRSIRT3 | |
| SCHEMBL24788062 | 0.68 | SPHK1 (0.48) | SIRT1 | |
| SCHEMBL22593910 | 0.67 | TRPV1 (0.46) | QRFPR | |
| SCHEMBL22593891 | 0.67 | TRPV1 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3617221-A1 | CYTOTOXIN AND CONJUGATE, USES OF SAME, AND PREPARATION METHOD THEREFOR | Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (CN) | 2020-03-04 | — | — | EP | disclosed |