Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MT-CO2 | P00403 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.33 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.33 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.32 |
| ▸ | CHRNG | P07510 | 1/20 | 0.32 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | CHRND | Q07001 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2178410 | 0.85 | CHRNB2 (0.37) | MT-CO2CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL2354020 | 0.82 | CYP19A1 (0.36) | CYP19A1ARGAA | |
| SCHEMBL2180329 | 0.81 | CHRNB2 (0.34) | MT-CO2CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL2178837 | 0.77 | GAA (0.35) | MT-CO2GAA | |
| SCHEMBL3868314 | 0.76 | CHRNB2 (0.41) | MT-CO2CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL1163580 | 0.74 | MEN1 (0.44) | MT-CO2 | |
| SCHEMBL6650593 | 0.74 | CHRNB2 (0.42) | CHRNB2CHRNB4CHRNA3CHRNA4GPR119 | |
| SCHEMBL17878846 | 0.74 | KCNH2 (0.39) | GPR119EGLN2SLC6A2ABCB1SCN9A | |
| SCHEMBL12484843 | 0.72 | PDE4B (0.53) | — | |
| SCHEMBL922803 | 0.72 | MT-CO2 (0.46) | MT-CO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130289000-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS INC (US) | 2013-10-31 | — | — | US | disclosed |
| US-8470803-B2 | Boron-containing small molecules | ANACOR PHARMACEUTICALS, INC. (US) | 2013-06-25 | — | — | US | disclosed |
| US-20110166103-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. (US) | 2011-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110166103-A1 | BORON-CONTAINING SMALL MOLECULES | NFKBIA, BCL6B, TNF | MT-CO2 4815/4885CHRNB2 3527/4885CHRNB4 3916/4885 |
| US-20130289000-A1 | BORON-CONTAINING SMALL MOLECULES | NFKBIA, BCL6B, TNF | MT-CO2 4815/4885CHRNB2 3527/4885CHRNB4 3916/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.