Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | PYGL | P06737 | 2/20 | 0.39 |
| ▸ | VNN1 | O95497 | 7/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1712741 | 0.83 | PYGL (0.40) | PYGLVNN1DPP4DPP8USP30 | |
| SCHEMBL1307160 | 0.83 | PYGL (0.40) | PYGLVNN1DPP4DPP8USP30 | |
| SCHEMBL13939912 | 0.77 | CCR5 (0.44) | CCR5VNN1DPP4KCNH2DPP8 | |
| SCHEMBL1309093 | 0.76 | L3MBTL3 (0.35) | PYGL | |
| SCHEMBL404146 | 0.76 | L3MBTL3 (0.35) | PYGL | |
| SCHEMBL13955505 | 0.76 | L3MBTL3 (0.35) | PYGL | |
| SCHEMBL21772872 | 0.75 | VNN1 (0.47) | CCR5VNN1DPP4KCNH2DPP8 | |
| SCHEMBL1712685 | 0.74 | BCHE (0.41) | DPP4 | |
| SCHEMBL21201804 | 0.73 | PYGL (0.33) | PYGL | |
| SCHEMBL21201850 | 0.73 | ADH1C (0.47) | PYGL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020043658-A1 | HETEROAROMATIC COMPOUNDS AS VANIN INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2020-03-05 | — | — | WO | disclosed |