Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.46 |
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31385340 | 0.82 | MAOA (0.55) | MAOAMAOBSMN1; SMN2CHRM2HRH3 | |
| SCHEMBL7749926 | 0.82 | MAOA (0.55) | MAOAMAOBSMN1; SMN2CHRM2HRH3 | |
| SCHEMBL19214858 | 0.81 | CYP1A2 (0.46) | MAOAMAOBSMN1; SMN2CHRM2HRH3 | |
| SCHEMBL16741775 | 0.81 | MAOA (0.47) | MAOAMAOBSMN1; SMN2CHRM2HRH3 | |
| SCHEMBL18893405 | 0.79 | MAOA (0.49) | MAOAMAOBSMN1; SMN2CHRM2HRH3 | |
| SCHEMBL16225118 | 0.75 | MAOA (0.51) | MAOAMAOBSMN1; SMN2CHRM2HRH3 | |
| SCHEMBL31536403 | 0.74 | SMN1; SMN2 (0.58) | SMN1; SMN2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL7440376 | 0.74 | ALDH1A1 (0.47) | SMN1; SMN2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL19465295 | 0.74 | CYP1A2 (0.46) | MAOAMAOBSMN1; SMN2HRH3ALDH1A1 | |
| SCHEMBL19176757 | 0.74 | FDPS (0.45) | MAOAMAOBSMN1; SMN2HRH3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220204452-A1 | ANTIMALARIAL COMPOUNDS | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. | 2022-06-30 | — | — | US | disclosed |
| US-11236195-B2 | Corrosion-indicating materials and methods of making and using the same | SAUDI ARABIAN OIL COMPANY (SA) | 2022-02-01 | — | — | US | disclosed |
| US-20200071308-A1 | Benzene, Pyridine, and Pyridazine Derivatives | ESANEX INC (US) | 2020-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200071308-A1 | Benzene, Pyridine, and Pyridazine Derivatives | CDK4, P2RX4, MKI67 | MAOA 2332/4885MAOB 1117/4885SMN1; SMN2 3208/4885 |
| US-20220204452-A1 | ANTIMALARIAL COMPOUNDS | H1-3, FPR3, NHERF1 | MAOA 1480/4885MAOB 729/4885SMN1; SMN2 1026/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.