Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | MMP1 | P03956 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | MMP9 | P14780 | 2/20 | 0.40 |
| ▸ | MMP8 | P22894 | 2/20 | 0.40 |
| ▸ | MMP13 | P45452 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 2/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL2500523 | 0.97 | CA2 (0.42) | CA2CA1MMP1MMP2MMP9 | |
| Potassium Ion SCHEMBL2499167 | 0.93 | CA2 (0.35) | CA2CA1MMP1MMP2MMP9 | |
| Lithium Ion SCHEMBL3745424 | 0.93 | CA2 (0.40) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL2499938 | 0.93 | CA2 (0.42) | CA2CA1MMP1MMP2MMP9 | |
| Potassium Ion SCHEMBL126340 | 0.91 | CA2 (0.52) | CA2CA1MMP1MMP2MMP9 | |
| Potassium Ion SCHEMBL29395213 | 0.90 | CA1 (0.33) | CA2CA1MMP1MMP2MMP9 | |
| Potassium Ion SCHEMBL9855988 | 0.89 | CA2 (0.34) | CA2CA1MMP1MMP2MMP9 | |
| Potassium Ion SCHEMBL2354990 | 0.89 | CA2 (0.52) | CA2CA1MMP1MMP2MMP9 | |
| Potassium Ion SCHEMBL4443223 | 0.89 | CA2 (0.54) | CA2CA1MMP1MMP2MMP9 | |
| Potassium Ion SCHEMBL4056625 | 0.89 | CA2 (0.54) | CA2CA1MMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4479476-A1 | FLAME-RETARDANT POLYCARBONATE COMPOSITION | Covestro Deutschland AG (DE) | 2024-12-25 | — | — | EP | disclosed |
| CN-118696093-A | Flame retardant polycarbonate compositions | 科思创德国股份有限公司 | 2024-09-24 | — | — | CN | disclosed |
| EP-4204492-B1 | HYDROLYSIS-RESISTANT POLYCARBONATE COMPOSITION | COVESTRO DEUTSCHLAND AG (DE) | 2024-06-26 | — | — | EP | disclosed |
| US-20230312918-A1 | Hydrolysis-Resistant Polycarbonate Composition | COVESTRO DEUTSCHLAND AG (DE) | 2023-10-05 | — | — | US | disclosed |
| WO-2023156339-A1 | FLAME-RETARDANT POLYCARBONATE COMPOSITION | COVESTRO DEUTSCHLAND AG (DE) | 2023-08-24 | — | — | WO | disclosed |
| EP-4230697-A1 | HYDROLYSIS-RESISTANT POLYCARBONATE COMPOSITION | Covestro Deutschland AG (DE) | 2023-08-23 | — | — | EP | disclosed |
| CN-116096818-A | Hydrolysis-resistant polycarbonate compositions | 科思创德国股份有限公司 | 2023-05-09 | — | — | CN | disclosed |
| WO-2022043424-A1 | HYDROLYSIS-RESISTANT POLYCARBONATE COMPOSITION | COVESTRO DEUTSCHLAND AG (DE) | 2022-03-03 | — | — | WO | disclosed |
| EP-2610308-B1 | USE OF POLYCARBOSILANE AS DISPERSANT FOR FLUOROPOLYMERS IN POLYCARBONATE RESINS | MITSUBISHI ENG PLASTICS CORP (JP) | 2020-07-15 | — | — | EP | disclosed |
| EP-2743314-B1 | POLYCARBONATE RESIN COMPOSITION AND MOLDED OBJECT THEREOF | MITSUBISHI ENG PLASTICS CORP (JP) | 2020-02-26 | — | — | EP | disclosed |
| US-7223891-B2 | Solid-phase preparation of [18F] fluorohaloalkanes | HAMMERSMITH IMANET LTD. (GB) | 2007-05-29 | — | — | US | disclosed |
| EP-1572602-B1 | SOLID-PHASE PREPARATION OF [18F] FLUOROHALOALKANES | HAMMERSMITH IMANET LTD (GB) | 2007-05-09 | — | — | EP | disclosed |
| WO-2007007175-A2 | PHOTOACTIVE COMPOUNDS | AZ ELECTRONIC MATERIAL USA CORP. (DE) | 2007-01-18 | — | — | WO | disclosed |
| US-20070015084-A1 | Iodonium or sulfonium di-(tetrafluoroethyl sulfonate) ether acid generators; imaging negative and positive patterns in semiconductors and photoresists; microlithography; high photosensitivity | MERCK PATENT GMBH (DE) | 2007-01-18 | — | — | US | disclosed |
| US-20060069294-A1 | Solid-phase preparation of [18f] fluorohaloalkanes | HAMMERSMITH IMANET LLIMITED (GB) | 2006-03-30 | — | — | US | disclosed |
| EP-1572602-A1 | SOLID-PHASE PREPARATION OF [18F] FLUOROHALOALKANES | Hammersmith Imanet Limited (GB) | 2005-09-14 | — | — | EP | disclosed |
| US-20040236085-A1 | Solid-phase nucleophilic fluorination | GE HEALTHCARE LIMITED (GB) | 2004-11-25 | — | — | US | disclosed |
| WO-2004056726-A1 | SOLID-PHASE PREPARATION OF [18F]FLUOROHALOALKANES | HAMMERSMITH IMANET LIMITED (GB) | 2004-07-08 | — | — | WO | disclosed |
| EP-1418950-A1 | SOLID-PHASE NUCLEOPHILIC FLUORINATION | Amersham plc (GB) | 2004-05-19 | — | — | EP | disclosed |
| WO-2003002157-A1 | SOLID-PHASE NUCLEOPHILIC FLUORINATION | AMERSHAM PLC (GB) | 2003-01-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040236085-A1 | Solid-phase nucleophilic fluorination | NAA15, SAMHD1, TMEM14C | CA2 3657/4885CA1 1317/4885MMP1 2331/4885 |
| US-20060069294-A1 | Solid-phase preparation of [18f] fluorohaloalkanes | SLCO2A1, SLCO2B1, FES | CA2 1761/4885CA1 371/4885MMP1 791/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.