Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCG | P01275 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.34 |
| ▸ | PDE2A | O00408 | 2/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.32 |
| ▸ | MERTK | Q12866 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 2/20 | 0.32 |
| ▸ | PARP1 | P09874 | 7/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.31 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21795643 | 0.84 | DDB1 (0.38) | FFAR4ACACBHDAC4 | |
| SCHEMBL15420780 | 0.83 | GCG (0.38) | GCGFFAR4PDE2APDE10AAXL | |
| SCHEMBL15420816 | 0.78 | PDE2A (0.34) | GCGFFAR4PDE2APDE10AACACB | |
| SCHEMBL21795640 | 0.76 | PARP15 (0.42) | PARP2ALDH1A1 | |
| SCHEMBL21795659 | 0.75 | NPC1 (0.39) | FFAR4PARP2 | |
| SCHEMBL21795636 | 0.74 | XDH (0.39) | FFAR4DGAT1 | |
| SCHEMBL21795648 | 0.74 | XDH (0.39) | FFAR4DGAT1 | |
| SCHEMBL12989202 | 0.73 | HRH3 (0.36) | AXLMERTKACACBDDX3XALDH1A1 | |
| SCHEMBL12989204 | 0.73 | HRH3 (0.36) | AXLMERTKACACBDDX3XALDH1A1 | |
| SCHEMBL21795658 | 0.72 | HDAC1 (0.39) | FFAR4HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2694472-B1 | SULFONAMIDE DERIVATIVE AND USE THEREOF | TAKEDA PHARMACEUTICALS CO (JP) | 2020-03-11 | — | — | EP | disclosed |