Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 3/20 | 0.36 |
| ▸ | PARP15 | Q460N3 | 4/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.35 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ATF4 | P18848 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21795648 | 0.88 | XDH (0.39) | XDHATF4FFAR4GPR119 | |
| SCHEMBL21795636 | 0.88 | XDH (0.39) | XDHATF4FFAR4GPR119 | |
| SCHEMBL21795640 | 0.81 | PARP15 (0.42) | SMN1; SMN2PARP15PARP10PARP2MAPT | |
| SCHEMBL21795663 | 0.80 | XDH (0.39) | NPC1XDHFFAR4GPR119 | |
| SCHEMBL15420805 | 0.80 | NPC1 (0.39) | NPC1RAB9ASMN1; SMN2HSD17B10XDH | |
| SCHEMBL21795638 | 0.79 | KDM4E (0.42) | XDHPARP2GPR119 | |
| Hydrochloric Acid SCHEMBL12987993 | 0.78 | NPC1 (0.44) | NPC1RAB9ASMN1; SMN2HSD17B10XDH | |
| SCHEMBL21795670 | 0.78 | KCNH2 (0.35) | PARP15PARP10FFAR4GPR119 | |
| SCHEMBL21795667 | 0.76 | FFAR4 (0.37) | FFAR4MAPK1 | |
| SCHEMBL21795642 | 0.75 | GCG (0.34) | PARP2FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2694472-B1 | SULFONAMIDE DERIVATIVE AND USE THEREOF | TAKEDA PHARMACEUTICALS CO (JP) | 2020-03-11 | — | — | EP | disclosed |