Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP15 | Q460N3 | 4/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.42 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL15420637 | 0.82 | PARP15 (0.45) | PARP15PARP10PARP2L3MBTL1ALDH1A1 | |
| SCHEMBL21795659 | 0.81 | NPC1 (0.39) | PARP15PARP10PARP2SMN1; SMN2MAPT | |
| SCHEMBL21795643 | 0.78 | DDB1 (0.38) | LMNA | |
| SCHEMBL21795663 | 0.77 | XDH (0.39) | — | |
| SCHEMBL21795648 | 0.77 | XDH (0.39) | MAOB | |
| SCHEMBL21795636 | 0.77 | XDH (0.39) | MAOB | |
| SCHEMBL15420332 | 0.77 | ALDH1A1 (0.42) | L3MBTL1ALDH1A1KDM4EGAALMNA | |
| SCHEMBL21795638 | 0.76 | KDM4E (0.42) | PARP2L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL21795642 | 0.76 | GCG (0.34) | PARP2ALDH1A1 | |
| SCHEMBL21795658 | 0.75 | HDAC1 (0.39) | KDM4EGAASMN1; SMN2MAPTMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2694472-B1 | SULFONAMIDE DERIVATIVE AND USE THEREOF | TAKEDA PHARMACEUTICALS CO (JP) | 2020-03-11 | — | — | EP | disclosed |