Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | KAT7 | O95251 | 1/20 | 0.36 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.36 |
| ▸ | OXTR | P30559 | 3/20 | 0.35 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.35 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 2/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | F5 | P12259 | 1/20 | 0.31 |
| ▸ | BRSK2 | Q8IWQ3 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21795642 | 0.84 | GCG (0.34) | FFAR4HDAC4ACACB | |
| SCHEMBL15420757 | 0.82 | DDB1 (0.41) | DDB1CRBNKAT7KAT5OXTR | |
| SCHEMBL21795640 | 0.78 | PARP15 (0.42) | LMNA | |
| SCHEMBL15441678 | 0.76 | KAT7 (0.39) | DDB1CRBNKAT7KAT5OXTR | |
| SCHEMBL15420022 | 0.76 | KAT7 (0.39) | DDB1CRBNKAT7KAT5OXTR | |
| SCHEMBL21795658 | 0.74 | HDAC1 (0.39) | FFAR4HTTNPC1RAB9A | |
| SCHEMBL21795659 | 0.73 | NPC1 (0.39) | FFAR4NPC1RAB9A | |
| SCHEMBL21795663 | 0.72 | XDH (0.39) | FFAR4NPC1GRM5 | |
| SCHEMBL21795648 | 0.72 | XDH (0.39) | FFAR4 | |
| SCHEMBL21795636 | 0.72 | XDH (0.39) | FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2694472-B1 | SULFONAMIDE DERIVATIVE AND USE THEREOF | TAKEDA PHARMACEUTICALS CO (JP) | 2020-03-11 | — | — | EP | disclosed |