Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.44 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.44 |
| ▸ | FNTA | P49354 | 1/20 | 0.44 |
| ▸ | FNTB | P49356 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 6/20 | 0.43 |
| ▸ | CTSS | P25774 | 4/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 6/20 | 0.41 |
| ▸ | PPARG | P37231 | 5/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13571099 | 1.00 | GRIK1 (0.44) | GRIK1GRIK2FNTAFNTBMEN1 | |
| SCHEMBL29273137 | 1.00 | GRIK1 (0.44) | GRIK1GRIK2FNTAFNTBMEN1 | |
| SCHEMBL7359050 | 0.87 | MEN1 (0.46) | MEN1GAAKMT2ACTSKCTSS | |
| SCHEMBL212772 | 0.86 | CTSK (0.47) | CTSKCTSSCTSLCTSBSMN1; SMN2 | |
| SCHEMBL2728681 | 0.86 | CTSK (0.47) | CTSKCTSSCTSLCTSBSMN1; SMN2 | |
| SCHEMBL212773 | 0.86 | CTSK (0.47) | CTSKCTSSCTSLCTSBSMN1; SMN2 | |
| SCHEMBL1890772 | 0.83 | SMN1; SMN2 (0.44) | CTSKCTSSCTSLCTSBSMN1; SMN2 | |
| SCHEMBL12963013 | 0.82 | SMN1; SMN2 (0.44) | CTSKCTSSCTSLCTSBSMN1; SMN2 | |
| SCHEMBL30965306 | 0.82 | SMN1; SMN2 (0.44) | CTSKCTSSCTSLCTSBSMN1; SMN2 | |
| SCHEMBL1128594 | 0.82 | SMN1; SMN2 (0.44) | CTSKCTSSCTSLCTSBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9308282-B2 | [F-18]-labelled L-glutamic acid and L-glutamine derivatives (I), their use and processes for their preparation | PIRAMAL IMAGING SA (CH) | 2016-04-12 | — | — | US | disclosed |
| US-9238631-B2 | Radiolabeled amino acids for diagnostic imaging | PIRAMAL IMAGING SA (CH) | 2016-01-19 | — | — | US | disclosed |
| US-20150011773-A1 | RADIOLABELED AMINO ACIDS FOR DIAGNOSTIC IMAGING | PIRAMAL IMAGING SA (CH) | 2015-01-08 | — | — | US | disclosed |
| US-20140154183-A1 | NOVEL [F-18]-LABELLED L-GLUTAMIC ACID AND L-GLUTAMINE DERIVATIVES (I), THEIR USE AND PROCESSES FOR THEIR PREPARATION | LIFE MOLECULAR IMAGING SA (CH) | 2014-06-05 | — | — | US | disclosed |
| US-20130149243-A1 | METHOD FOR PRODUCTION OF F-18 LABELED GLUTAMIC ACID DERIVATIVES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-06-13 | — | — | US | disclosed |
| US-20130034497-A1 | IODINE-LABELED HOMOGLUTAMIC ACID AND GLUTAMIC ACID DERIVATIVES | PIRAMAL IMAGING SA (CH) | 2013-02-07 | — | — | US | disclosed |
| EP-2520556-A1 | Radiolabeled amino acids for diagnostic imaging | Bayer Pharma Aktiengesellschaft (DE) | 2012-11-07 | — | — | EP | disclosed |
| EP-2501663-A2 | METHOD FOR PRODUCTION OF F-18 LABELED GLUTAMIC ACID DERIVATIVES | Piramal Imaging SA (CH) | 2012-09-26 | — | — | EP | disclosed |
| US-20110165076-A1 | NOVEL [F-18]- LABELLED L-GLUTAMIC ACID AND L-GLUTAMINE DERIVATIVES (I), USE THEREOF AND METHOD FOR THEIR PRODUCTION | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2011-07-07 | — | — | US | disclosed |
| US-20100290991-A1 | NOVEL [F-18]-LABELLED L-GLUTAMIC ACID AND L-GLUTAMINE DERIVATIVES (I), THEIR USE AND PROCESSES FOR THEIR PREPARATION | BAYER SCHERING PHARMA AG (DE) | 2010-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130149243-A1 | METHOD FOR PRODUCTION OF F-18 LABELED GLUTAMIC ACID DERIVATIVES | GLUL, SLC18A2, SLC1A2 | GRIK1 46/4885GRIK2 19/4885FNTA 140/4885 |
| US-20150011773-A1 | RADIOLABELED AMINO ACIDS FOR DIAGNOSTIC IMAGING | SLC1A5, SLC6A19, BCAT2 | GRIK1 2290/4885GRIK2 2502/4885FNTA 511/4885 |
| US-20100290991-A1 | NOVEL [F-18]-LABELLED L-GLUTAMIC ACID AND L-GLUTAMINE DERIVATIVES (I), THEIR USE AND PROCESSES FOR THEIR PREPARATION | GLUL, QPCT, SLC1A2 | GRIK1 40/4885GRIK2 37/4885FNTA 354/4885 |
| US-20130034497-A1 | IODINE-LABELED HOMOGLUTAMIC ACID AND GLUTAMIC ACID DERIVATIVES | GLUL, GCG, GLS | GRIK1 28/4885GRIK2 34/4885FNTA 444/4885 |
| US-20140154183-A1 | NOVEL [F-18]-LABELLED L-GLUTAMIC ACID AND L-GLUTAMINE DERIVATIVES (I), THEIR USE AND PROCESSES FOR THEIR PREPARATION | GLUL, QPCT, SLC1A2 | GRIK1 40/4885GRIK2 37/4885FNTA 354/4885 |
| US-20110165076-A1 | NOVEL [F-18]- LABELLED L-GLUTAMIC ACID AND L-GLUTAMINE DERIVATIVES (I), USE THEREOF AND METHOD FOR THEIR PRODUCTION | GLUL, QPCT, GFPT1 | GRIK1 42/4885GRIK2 39/4885FNTA 268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.