Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | BAX | Q07812 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 4/20 | 0.39 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1451040 | 0.87 | LTA4H (0.60) | LTA4HTSHRMAOBNR1H2BAX | |
| SCHEMBL28354760 | 0.85 | MAOA (0.50) | LTA4HCYP1A2CYP2C9CYP2C19MAOB | |
| SCHEMBL28928700 | 0.80 | HTR2A (0.40) | MAOBMAOAMEN1KMT2A | |
| SCHEMBL811027 | 0.78 | LTA4H (0.60) | LTA4HTSHRCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL3789307 | 0.78 | LTA4H (0.60) | LTA4HTSHRCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9638221 | 0.78 | LTA4H (0.48) | LTA4HTSHRMAOBNR1H2BAX | |
| SCHEMBL9685550 | 0.78 | LTA4H (0.48) | LTA4HTSHRMAOBNR1H2BAX | |
| SCHEMBL9685855 | 0.78 | LTA4H (0.59) | LTA4HTSHRMAOBNR1H2BAX | |
| SCHEMBL3790523 | 0.76 | LTA4H (0.57) | LTA4HTSHRCYP1A2CYP3A4CYP2C9 | |
| Diphenylether SCHEMBL1118926 | 0.74 | LTA4H (0.71) | LTA4HTSHRCYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115551839-B | Heteroaryl-triazole compounds as pesticides | 拜耳公司 | 2024-06-04 | — | — | CN | disclosed |
| CN-113454066-B | Process for preparing 6- (1-propenoylpiperidin-4-yl) -2- (4-phenoxyphenyl) nicotinamide | 北京诺诚健华医药科技有限公司 | 2024-02-09 | — | — | CN | disclosed |
| US-20230148601-A1 | NOVEL HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2023-05-18 | — | — | US | disclosed |
| CN-115551839-A | Heteroaryl-triazole compounds as pesticides | 拜耳公司 | 2022-12-30 | — | — | CN | disclosed |
| EP-4107151-A1 | HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES | Bayer Aktiengesellschaft (DE) | 2022-12-28 | — | — | EP | disclosed |
| CN-113454066-A | Process for the preparation of 6- (1-acryloylpiperidin-4-yl) -2- (4-phenoxyphenyl) nicotinamide | 北京诺诚健华医药科技有限公司 | 2021-09-28 | — | — | CN | disclosed |
| US-8748426-B2 | Inhibitors of diacylglycerol acyl transferase | Piramal Enterprises Limited (IN) | 2014-06-10 | — | — | US | disclosed |
| US-20120289505-A1 | INHIBITORS OF DIACYLGLYCEROL ACYL TRANSFERASE | Piramal Enterprises Limited (IN) | 2012-11-15 | — | — | US | disclosed |
| CN-102781915-A | Diacylglycerol acyltransferase inhibitors | PIRAMAL LIFE SCIENCES LTD | 2012-11-14 | — | — | CN | disclosed |
| EP-2519500-A1 | INHIBITORS OF DIACYLGLYCEROL ACYL TRANSFERASE | Piramal Healthcare Ltd. (IN) | 2012-11-07 | — | — | EP | disclosed |
| EP-0224024-B1 | SILANE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AGENTS CONTAINING THEM AND THEIR USE AS PESTICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-06-20 | — | — | EP | disclosed |
| CN-1036570-A | The new silylation sulfide of new alkyl sulfur compounds of azepine and azepine, they the preparation method, contain their preparation and they are as the application of sterilant | HOECHST AG (DE) | 1989-10-25 | — | — | CN | disclosed |
| EP-0336199-A1 | Azaneophyl and silazaneophyl sulfides, process for their preparation, agents containing them, and their use as pesticides | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-10-11 | — | — | EP | disclosed |
| US-4864027-A | INSECTICIDES, NEMATOCIDES, MITICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-09-05 | — | — | US | disclosed |
| EP-0288810-A1 | Heterocyclic neophane analogs, processes for their preparation and their use as pesticides | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-11-02 | — | — | EP | disclosed |
| CN-88102112-A | Heterocyclic neophenan analogs, process for their preparation and their use as pesticides | — | 1988-10-26 | — | — | CN | disclosed |
| US-4775664-A | INSECTICIDES, MITICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-10-04 | — | — | US | disclosed |
| CN-87102981-A | Novel silane derivatives, process for their preparation, formulations containing them and their use as pesticides | — | 1988-03-02 | — | — | CN | disclosed |
| EP-0249015-A1 | Silane derivatives, process for their preparation, agents containing them, and their use as pesticides | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-12-16 | — | — | EP | disclosed |
| CN-86107292-A | Novel silane derivatives, process for their preparation, formulations containing them and their use as pesticides | — | 1987-07-29 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230148601-A1 | NOVEL HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES | PRXL2A, GLRX3, CYP4F3 | LTA4H 1860/4885TSHR 109/4885CYP1A2 75/4885 |
| US-20120289505-A1 | INHIBITORS OF DIACYLGLYCEROL ACYL TRANSFERASE | DGAT1, DGAT2, LCAT | LTA4H 782/4885TSHR 3334/4885CYP1A2 1241/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.