Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.37 |
| ▸ | F2R | P25116 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14229099 | 0.76 | TP53 (0.51) | TP53HTTESR1HPGDALDH1A1 | |
| SCHEMBL622138 | 0.75 | TP53 (0.62) | TP53HTTSMN1; SMN2HPGDALDH1A1 | |
| Methane SCHEMBL7619527 | 0.74 | HTT (0.40) | TP53HTTESR1SMN1; SMN2 | |
| SCHEMBL7995828 | 0.73 | CES2 (0.39) | BCL2A1ALDH1A1 | |
| SCHEMBL9524378 | 0.68 | TP53 (0.41) | TP53HTTESR1SMN1; SMN2F2R | |
| SCHEMBL3370588 | 0.68 | HTT (0.44) | HTTESR1HPGD | |
| SCHEMBL10566045 | 0.68 | TP53 (0.49) | TP53HTTHPGDALDH1A1 | |
| SCHEMBL27903588 | 0.68 | ALDH1A1 (0.49) | TP53OPRM1ALDH1A1 | |
| SCHEMBL11538601 | 0.68 | ESR1 (0.48) | TP53HTTESR1SMN1; SMN2BCL2A1 | |
| 1,2-Dichlorobenzene SCHEMBL27977202 | 0.67 | TSHR (0.58) | TP53HTTSMN1; SMN2F2RHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140162906-A1 | Pesticide Biomarker | NAGY JON OWEN (US) | 2014-06-12 | — | — | US | disclosed |
| US-20110166043-A1 | BIOMARKER DETECTION-2 | ATERIS TECHNOLOGIES, LLC | 2011-07-07 | — | — | US | disclosed |
| US-20100041077-A1 | PESTICIDE BIOMARKER | ATERIS TECHNOLOGIES, LLC | 2010-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110166043-A1 | BIOMARKER DETECTION-2 | CPB2, NAALAD2, PRSS2 | TP53 1225/4885HTT 4537/4885ESR1 3138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.