Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | STAT1 | P42224 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3124093 | 0.81 | LMNA (0.42) | LMNAALDH1A1RAB9AL3MBTL1MEN1 | |
| SCHEMBL2652124 | 0.78 | ALDH1A1 (0.49) | LMNAALDH1A1RAB9AL3MBTL1MEN1 | |
| SCHEMBL2651752 | 0.77 | ALDH1A1 (0.51) | LMNAALDH1A1RAB9AL3MBTL1MEN1 | |
| SCHEMBL2090920 | 0.77 | RAB9A (0.59) | LMNAALDH1A1RAB9AL3MBTL1MEN1 | |
| SCHEMBL21812656 | 0.77 | LMNA (0.38) | LMNAALDH1A1RAB9AL3MBTL1MEN1 | |
| SCHEMBL12492865 | 0.75 | LMNA (1.00) | LMNAALDH1A1RAB9AL3MBTL1MEN1 | |
| SCHEMBL972897 | 0.74 | ALDH1A1 (0.49) | LMNAALDH1A1RAB9AL3MBTL1MEN1 | |
| SCHEMBL25309164 | 0.74 | MEN1 (0.49) | LMNAALDH1A1MEN1SMN1; SMN2HTT | |
| SCHEMBL29444684 | 0.73 | ALDH1A1 (0.48) | LMNAALDH1A1RAB9AL3MBTL1MEN1 | |
| SCHEMBL102234 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010036632-A1 | AZAINDAZOLE COMPOUNDS AS CCR1 RECEPTOR ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-01 | — | — | WO | disclosed |