Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.73 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.73 |
| ▸ | PI4KA | P42356 | 2/20 | 0.73 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.73 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.73 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.73 |
| ▸ | DPP4 | P27487 | 1/20 | 0.73 |
| ▸ | MEN1 | O00255 | 1/20 | 0.73 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.73 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.73 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.73 |
| ▸ | GAPDH | P04406 | 1/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.73 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.73 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.73 |
| ▸ | STAT6 | P42226 | 1/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.73 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.73 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23928781 | 0.93 | ADORA3 (0.72) | ADORA3ADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL28991005 | 0.93 | ADORA3 (0.72) | ADORA3ADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL30274521 | 0.93 | ADORA3 (0.72) | ADORA3ADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL28991009 | 0.93 | ADORA3 (0.72) | ADORA3ADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL28804979 | 0.92 | ADORA3 (0.75) | ADORA3ADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL7611755 | 0.91 | ADORA3 (0.73) | ADORA3ADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL16174422 | 0.91 | ADORA3 (0.73) | ADORA3ADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL14424485 | 0.91 | ADORA3 (0.73) | ADORA3ADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL7611746 | 0.91 | ADORA3 (0.73) | ADORA3ADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL6898326 | 0.90 | ADORA3 (0.72) | ADORA3ADORA1PI4KAPI4K2BPI4K2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11918644-B2 | Varicella zoster virus (VZV) vaccine | MODERNATX, INC. (US) | 2024-03-05 | — | — | US | disclosed |
| US-20230323371-A1 | POLYNUCLEOTIDES ENCODING ALPHA-GALACTOSIDASE A FOR THE TREATMENT OF FABRY DISEASE | MODERNATX, INC. | 2023-10-12 | — | — | US | disclosed |
| US-20220409720-A1 | VARICELLA ZOSTER VIRUS (VZV) VACCINE | MODERNATX, INC. (US) | 2022-12-29 | — | — | US | disclosed |
| US-11421011-B2 | Polynucleotides encoding tethered interleukin-12 (IL12) polypeptides and uses thereof | MODERNATX, INC. (US) | 2022-08-23 | — | — | US | disclosed |
| US-20220047518-A1 | PEG LIPIDS AND USES THEREOF | Moderna TX, Inc. (US) | 2022-02-17 | — | — | US | disclosed |
| US-20210206818-A1 | MESSENGER RIBONUCLEIC ACIDS FOR THE PRODUCTION OF INTRACELLULAR BINDING POLYPEPTIDES AND METHODS OF USE THEREOF | MODERNATX, INC. | 2021-07-08 | — | — | US | disclosed |
| US-11003366-B2 | Methods of using OX40 ligand encoding polynucleotides | MODERNATX, INC. (US) | 2021-05-11 | — | — | US | disclosed |
| US-20200102363-A1 | POLYNUCLEOTIDES ENCODING TETHERED INTERLEUKIN-12 (IL12) POLYPEPTIDES AND USES THEREOF | MODERNATX, INC. (US) | 2020-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11421011-B2 | Polynucleotides encoding tethered interleukin-12 (IL12) polypeptides and uses thereof | IL2, PRR12, IL2RA | ADORA3 4297/4885ADORA1 4360/4885PI4KA 1626/4885 |
| US-20220047518-A1 | PEG LIPIDS AND USES THEREOF | LIPA, LIPG, LNPEP | ADORA3 4579/4885ADORA1 4735/4885PI4KA 1904/4885 |
| US-20220409720-A1 | VARICELLA ZOSTER VIRUS (VZV) VACCINE | RNMT, VAC14, IRF3 | ADORA3 3810/4885ADORA1 4377/4885PI4KA 1587/4885 |
| US-20200102363-A1 | POLYNUCLEOTIDES ENCODING TETHERED INTERLEUKIN-12 (IL12) POLYPEPTIDES AND USES THEREOF | IL2, PRR12, IL2RA | ADORA3 4297/4885ADORA1 4360/4885PI4KA 1626/4885 |
| US-20230323371-A1 | POLYNUCLEOTIDES ENCODING ALPHA-GALACTOSIDASE A FOR THE TREATMENT OF FABRY DISEASE | GBA1, GAA, GLA | ADORA3 2097/4885ADORA1 4004/4885PI4KA 1255/4885 |
| US-11918644-B2 | Varicella zoster virus (VZV) vaccine | RNMT, VAC14, IRF3 | ADORA3 3810/4885ADORA1 4377/4885PI4KA 1587/4885 |
| US-20210206818-A1 | MESSENGER RIBONUCLEIC ACIDS FOR THE PRODUCTION OF INTRACELLULAR BINDING POLYPEPTIDES AND METHODS OF USE THEREOF | PABPC4, HNRNPAB, PABPC1 | ADORA3 3304/4885ADORA1 4170/4885PI4KA 1915/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.