Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29568932 | 1.00 | CA12 (0.38) | CA12CA1CA2CA9LTA4H | |
| Hydrochloric Acid SCHEMBL15269240 | 0.98 | CA12 (0.37) | CA12CA1CA2CA9LTA4H | |
| Dioxane SCHEMBL23674613 | 0.92 | SMN1; SMN2 (0.40) | CA12CA1CA2CA9LTA4H | |
| SCHEMBL3457558 | 0.81 | — | — | |
| SCHEMBL5033603 | 0.72 | — | — | |
| SCHEMBL220683 | 0.70 | — | — | |
| SCHEMBL1595435 | 0.70 | CA12 (0.38) | CA12CA1CA2CA9LTA4H | |
| SCHEMBL2317954 | 0.70 | LTA4H (0.38) | CA12CA1CA2CA9LTA4H | |
| Pyrazine SCHEMBL22491600 | 0.67 | NOTUM (0.38) | MAPTLMNAHTTSMN1; SMN2NPC1 | |
| SCHEMBL7609642 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 150 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2336315-B1 | Enzymatic encoding methods for efficient synthesis of large libraries | NUEVOLUTION AS (DK) | 2017-07-19 | — | — | EP | claimed |
| EP-2336315-A2 | Enzymatic encoding methods for efficient synthesis of large libraries | Nuevolution A/S (DK) | 2011-06-22 | — | — | EP | claimed |
| US-6987117-B2 | Antidepressant azaheterocyclylmethyl derivatives of 1,4-dioxino[2,3-b]pyridine | WYETH (US) | 2006-01-17 | — | — | US | claimed |
| US-20040058953-A1 | Antidepressant azaheterocyclylmethyl derivatives of 1,4-dioxino[2,3-b]pyridine | TRAN MEGAN (US) | 2004-03-25 | — | — | US | claimed |
| US-6656950-B2 | For therapy of depression, obsessive compulsive disorder, panic attacks, generalized anxiety disorder, social anxiety disorder, sexual dysfunction, eating disorders, obesity, addictive disorders caused by ethanol or cocaine abuse | WYETH | 2003-12-02 | — | — | US | claimed |
| EP-0984934-B1 | NOVEL ORALLY ACTIVE IRON (III) CHELATORS | BTG INTERNAT LTD COMPANY NO 26 (GB) | 2003-01-08 | — | — | EP | claimed |
| US-20020183355-A1 | Antidepressant azaheterocyclylmethyl derivatives of 1,4-dioxino[2,3-b]pyridine | WYETH (US) | 2002-12-05 | — | — | US | claimed |
| WO-2002085911-A1 | ANTIDEPRESSANT AZAHETEROCYCLYLMETHYL DERIVATIVES OF 1,4-DIOXINO[2,3-b]PYRIDINE | WYETH (US) | 2002-10-31 | — | — | WO | claimed |
| EP-0559285-A1 | 1,4-Dioxino 2,3-b pyridine derivatives having serotonergic activity | Akzo Nobel N.V. (NL) | 1993-09-08 | — | — | EP | claimed |
| EP-0227932-A1 | Novel fused pyridine compounds, intermediates for the preparation of, and use of said compounds as herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1987-07-08 | — | — | EP | claimed |
| JP-6009641-A | — | — | None | — | — | JP | disclosed |
| US-20260091147-A1 | METHOD FOR DETECTING INNATE IMMUNE ACTION IN VIVO USING GPR84-PET | THE BOARD OF TRUSTEES OF THE LELAND STANDFORD JUNIOR UNIV (US) | 2026-04-02 | — | — | US | disclosed |
| WO-2025109540-A1 | MACROCYCLIC COMPOUNDS AS KIF18A INHIBITORS | AURIGENE ONCOLOGY LIMITED (IN) | 2025-05-30 | — | — | WO | disclosed |
| WO-2024220480-A2 | METHOD FOR DETECTING INNATE IMMUNE ACTION IN VIVO USING GPR84-PET | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2024-10-24 | — | — | WO | disclosed |
| US-11702652-B2 | Enzymatic encoding methods for efficient synthesis of large libraries | NUEVOLUTION A/S (DK) | 2023-07-18 | — | — | US | disclosed |
| EP-0559285-A1 | 1,4-Dioxino 2,3-b pyridine derivatives having serotonergic activity | Akzo Nobel N.V. (NL) | 1993-09-08 | — | — | EP | disclosed |
| EP-0559285-A1 | 1,4-Dioxino 2,3-b pyridine derivatives having serotonergic activity | Akzo Nobel N.V. (NL) | 1993-09-08 | — | — | EP | disclosed |
| EP-0559285-A1 | 1,4-Dioxino 2,3-b pyridine derivatives having serotonergic activity | Akzo Nobel N.V. (NL) | 1993-09-08 | — | — | EP | disclosed |
| EP-0227932-B1 | NOVEL FUSED PYRIDINE COMPOUNDS, INTERMEDIATES FOR THE PREPARATION OF, AND USE OF SAID COMPOUNDS AS HERBICIDAL AGENTS | AMERICAN CYANAMID COMPANY (US) | 1993-01-13 | — | — | EP | disclosed |
| EP-0227932-A1 | Novel fused pyridine compounds, intermediates for the preparation of, and use of said compounds as herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1987-07-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020183355-A1 | Antidepressant azaheterocyclylmethyl derivatives of 1,4-dioxino[2,3-b]pyridine | OPRD1, HSD17B11, OPRM1 | CA12 3854/4885CA1 2960/4885CA2 4524/4885 |
| US-20040058953-A1 | Antidepressant azaheterocyclylmethyl derivatives of 1,4-dioxino[2,3-b]pyridine | OPRD1, HSD17B11, OPRM1 | CA12 3854/4885CA1 2960/4885CA2 4524/4885 |
| US-20260091147-A1 | METHOD FOR DETECTING INNATE IMMUNE ACTION IN VIVO USING GPR84-PET | GPR84, GPR65, GPR88 | CA12 1044/4885CA1 1235/4885CA2 2710/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.