Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 4/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
| ▸ | TYMS | P04818 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29386231 | 1.00 | NPBWR1 (0.35) | NPBWR1MCHR1ALDH1A1KMT2ATP53 | |
| SCHEMBL29058622 | 0.90 | ALDH1A1 (0.36) | NPBWR1MCHR1ALDH1A1KMT2ATP53 | |
| SCHEMBL29382816 | 0.87 | NPBWR1 (0.41) | NPBWR1MCHR1ALDH1A1KMT2ALMNA | |
| SCHEMBL21835495 | 0.87 | NPBWR1 (0.41) | NPBWR1MCHR1ALDH1A1KMT2ALMNA | |
| SCHEMBL26163608 | 0.84 | ALDH1A1 (0.35) | ALDH1A1KMT2ALMNAMAPTHPGD | |
| SCHEMBL21835397 | 0.83 | MEN1 (0.33) | ALDH1A1KMT2ATP53LMNANPC1 | |
| SCHEMBL29443524 | 0.83 | MEN1 (0.33) | ALDH1A1KMT2ATP53LMNANPC1 | |
| SCHEMBL29058598 | 0.83 | LMNA (0.32) | ALDH1A1KMT2ATP53LMNAMAPT | |
| SCHEMBL28615978 | 0.76 | ALDH1A1 (0.38) | NPBWR1MCHR1ALDH1A1KMT2ALMNA | |
| SCHEMBL28612147 | 0.75 | ALDH1A1 (0.39) | NPBWR1MCHR1ALDH1A1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3856723-A1 | PYRIDAZINONE HERBICIDES AND PYRIDAZINONE INTERMEDIATES USED TO PREPARE A HERBICIDE | FMC Corporation (US) | 2021-08-04 | — | — | EP | disclosed |
| CN-113166075-A | Pyridazinone herbicides and pyridazinone intermediates for the preparation thereof | FMC公司 | 2021-07-23 | — | — | CN | disclosed |
| WO-2020069057-A1 | PYRIDAZINONE HERBICIDES AND PYRIDAZINONE INTERMEDIATES USED TO PREPARE A HERBICIDE | FMC CORPORATION (US) | 2020-04-02 | — | — | WO | disclosed |