Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29382816 | 1.00 | NPBWR1 (0.41) | NPBWR1MAPTSMN1; SMN2HSD11B1LMNA | |
| SCHEMBL29386231 | 0.87 | NPBWR1 (0.35) | NPBWR1MAPTSMN1; SMN2LMNAMCHR1 | |
| SCHEMBL21835493 | 0.87 | NPBWR1 (0.35) | NPBWR1MAPTSMN1; SMN2LMNAMCHR1 | |
| SCHEMBL20522633 | 0.86 | ALDH1A1 (0.41) | NPBWR1MAPTSMN1; SMN2HSD11B1LMNA | |
| SCHEMBL21835458 | 0.85 | HSD11B1 (0.38) | NPBWR1SMN1; SMN2HSD11B1RAB9AMEN1 | |
| SCHEMBL29383185 | 0.85 | HSD11B1 (0.38) | NPBWR1SMN1; SMN2HSD11B1RAB9AMEN1 | |
| SCHEMBL26163609 | 0.83 | SMN1; SMN2 (0.40) | NPBWR1SMN1; SMN2LMNAKMT2AALDH1A1 | |
| SCHEMBL21835554 | 0.83 | RAB9A (0.41) | NPBWR1MAPTSMN1; SMN2HSD11B1MCHR1 | |
| SCHEMBL29383170 | 0.83 | RAB9A (0.41) | NPBWR1MAPTSMN1; SMN2HSD11B1MCHR1 | |
| SCHEMBL29761324 | 0.82 | SMN1; SMN2 (0.37) | NPBWR1MAPTSMN1; SMN2LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3856723-A1 | PYRIDAZINONE HERBICIDES AND PYRIDAZINONE INTERMEDIATES USED TO PREPARE A HERBICIDE | FMC Corporation (US) | 2021-08-04 | — | — | EP | disclosed |
| CN-113166075-A | Pyridazinone herbicides and pyridazinone intermediates for the preparation thereof | FMC公司 | 2021-07-23 | — | — | CN | disclosed |
| WO-2020069057-A1 | PYRIDAZINONE HERBICIDES AND PYRIDAZINONE INTERMEDIATES USED TO PREPARE A HERBICIDE | FMC CORPORATION (US) | 2020-04-02 | — | — | WO | disclosed |