Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | CASP1 | P29466 | 2/20 | 0.35 |
| ▸ | CASP7 | P55210 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 5/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | AHR | P35869 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26163609 | 0.89 | SMN1; SMN2 (0.40) | ALDH1A1HPGDKDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL21835493 | 0.84 | NPBWR1 (0.35) | ALDH1A1HPGDKMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL29386231 | 0.84 | NPBWR1 (0.35) | ALDH1A1HPGDKMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL29058598 | 0.83 | LMNA (0.32) | ALDH1A1HPGDKDM4ECASP1CASP7 | |
| SCHEMBL29443524 | 0.79 | MEN1 (0.33) | ALDH1A1HPGDKDM4ECASP1CASP7 | |
| SCHEMBL21835397 | 0.79 | MEN1 (0.33) | ALDH1A1HPGDKDM4ECASP1CASP7 | |
| SCHEMBL23901770 | 0.78 | SMN1; SMN2 (0.38) | ALDH1A1KDM4EKMT2ASMN1; SMN2LMNA | |
| SCHEMBL29058622 | 0.74 | ALDH1A1 (0.36) | ALDH1A1HPGDKMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL29761331 | 0.73 | MMP1 (0.34) | ALDH1A1HPGDKDM4ECASP1CASP7 | |
| SCHEMBL29761328 | 0.72 | POLB (0.35) | KMT2AGAASMN1; SMN2LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230150945-A1 | ATROPISOMERS OF PYRIDAZINONE DERIVATIVES AS HERBICIDES | FMC CORPORATION | 2023-05-18 | — | — | US | disclosed |
| US-20230150945-A1 | ATROPISOMERS OF PYRIDAZINONE DERIVATIVES AS HERBICIDES | FMC CORPORATION | 2023-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230150945-A1 | ATROPISOMERS OF PYRIDAZINONE DERIVATIVES AS HERBICIDES | CYP1B1, CHRM2, CYP1A1 | ALDH1A1 488/4885HPGD 390/4885KDM4E 3446/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.