SCHEMBL29443524

SCHEMBL29443524

Cc1ccc2ccc(C)c(-c3c(O)c(Cl)nn(C)c3=O)c2c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.33
▸ KMT2A Q03164 1/20 0.33
▸ TYMS P04818 1/20 0.33
▸ CYP1A2 P05177 1/20 0.33
▸ CYP2A6 P11509 1/20 0.33
▸ KDM4E B2RXH2 5/20 0.32
▸ ALDH1A1 P00352 5/20 0.32
▸ CASP1 P29466 3/20 0.32
▸ CASP7 P55210 3/20 0.32
▸ RAB9A P51151 3/20 0.32
▸ NPC1 O15118 2/20 0.32
▸ TP53 P04637 2/20 0.32
▸ HPGD P15428 3/20 0.32
▸ DHODH Q02127 1/20 0.32
▸ MAPT P10636 5/20 0.32
▸ SMN1; SMN2 Q16637 3/20 0.32
▸ NPSR1 Q6W5P4 2/20 0.32
▸ LMNA P02545 3/20 0.32
▸ HSD17B10 Q99714 3/20 0.32
▸ MAPK1 P28482 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21835397 1.00 MEN1 (0.33) MEN1KMT2ATYMSCYP1A2CYP2A6
SCHEMBL25184883 0.90 MAPK8 (0.37) MEN1KMT2ATYMSKDM4ELMNA
SCHEMBL29058918 0.90 MEN1 (0.34) MEN1KMT2AKDM4EALDH1A1CASP1
SCHEMBL30834467 0.88 TSHR (0.38) KMT2ATYMSKDM4ETP53SMN1; SMN2
SCHEMBL25202984 0.86 HPGD (0.38) MEN1KMT2ACYP1A2CYP2A6KDM4E
SCHEMBL29695283 0.84 KMT2A (0.37) MEN1KMT2AKDM4EALDH1A1RAB9A
SCHEMBL29386231 0.83 NPBWR1 (0.35) KMT2ATYMSCYP1A2CYP2A6ALDH1A1
SCHEMBL21835493 0.83 NPBWR1 (0.35) KMT2ATYMSCYP1A2CYP2A6ALDH1A1
SCHEMBL26163608 0.79 ALDH1A1 (0.35) MEN1KMT2AKDM4EALDH1A1CASP1
SCHEMBL29058598 0.78 LMNA (0.32) MEN1KMT2AKDM4EALDH1A1CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12435044-B2 Pyridazinone herbicides and pyridazinone intermediates used to prepare a herbicide FMC CORPORATION (US) 2025-10-07 — — US claimed
EP-4593598-A1 STORAGE-STABLE COMPOSITIONS INCLUDING BIXLOZONE AND BEFLUBUTAMID FMC Corporation (US) 2025-08-06 — — EP claimed
WO-2025103880-A1 HERBICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2025-05-22 — — WO claimed
EP-4554381-A1 HERBICIDAL COMPOSITION COMPRISING AZINE COMPOUNDS BASF SE (DE) 2025-05-21 — — EP claimed
CN-119894374-A Use of alkyl ether sulphates for improving the efficacy of herbicides 巴斯夫欧洲公司 2025-04-25 — — CN claimed
CN-119677410-A Herbicidal compositions comprising azine compounds 巴斯夫欧洲公司 2025-03-21 — — CN claimed
CN-113166075-B Pyridazinone herbicides and pyridazinone intermediates for preparing the same FMC公司 2024-10-25 — — CN claimed
WO-2024073019-A1 STORAGE-STABLE COMPOSITIONS INCLUDING BIXLOZONE AND B EFLUB UT AMID FMC CORPORATION (US) 2024-04-04 — — WO claimed
WO-2024056517-A1 USE OF AN ALKYLETHER SULFATE FOR IMPROVING THE EFFICACY OF HERBICIDES BASF SE (DE) 2024-03-21 — — WO claimed
WO-2024012905-A1 HERBICIDAL COMPOSITION COMPRISING AZINE COMPOUNDS BASF SE (DE) 2024-01-18 — — WO claimed
CN-116568135-B Herbicidal derivatives Syngenta Crop Protection JSC (CH) 2026-05-26 — — CN disclosed
CN-122074074-A Pyridine and pyrimidine derivatives as herbicides 先正达农作物保护股份公司 2026-05-22 — — CN disclosed
US-20260123630-A1 COMPOSITIONS INCLUDING ENCAPSULATED BIXLOZONE AND NON ENCAPSULATED BIXLOZONE FMC CORP (US) 2026-05-07 — — US disclosed
EP-4702009-A1 HERBICIDAL DERIVATIVES Syngenta Crop Protection AG (CH) 2026-03-04 — — EP disclosed
WO-2026041514-A1 HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2026-02-26 — — WO disclosed
WO-2022101270-A1 HERBICIDAL N-HETEROARYL PYRAZOLE COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2022-05-19 — — WO disclosed
CN-114222733-A Cyclic diones as herbicidal compounds 先正达农作物保护股份公司 2022-03-22 — — CN disclosed
WO-2022053422-A1 HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2022-03-17 — — WO disclosed
CN-114144409-A Substituted pyridazinones as herbicides 先正达农作物保护股份公司 2022-03-04 — — CN disclosed
CN-114080385-A Herbicidal compounds 先正达农作物保护股份公司 2022-02-22 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12435044-B2 Pyridazinone herbicides and pyridazinone intermediates used to prepare a herbicide CBR3, CBR1, CYP4F3 MEN1 3526/4885KMT2A 4050/4885TYMS 1449/4885
US-20260123630-A1 COMPOSITIONS INCLUDING ENCAPSULATED BIXLOZONE AND NON ENCAPSULATED BIXLOZONE XPO5, XPO7, BECN1 MEN1 2810/4885KMT2A 4546/4885TYMS 2969/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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