SCHEMBL21836734

SCHEMBL21836734

O=C(O)/C=C/C(=O)NCCC(=O)O

nearest known ligand 0.52

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.52
TAAR1 Q96RJ0 6/20 0.52
LMNA P02545 2/20 0.46
CYP2D6 P10635 1/20 0.46
CYP2C19 P33261 1/20 0.46
ECE1 P42892 1/20 0.43
TSHR P16473 2/20 0.41
TP53 P04637 1/20 0.41
EGLN1 Q9GZT9 1/20 0.41
EGLN3 Q9H6Z9 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL543785 1.00 ALDH1A1 (0.52) ALDH1A1TAAR1LMNACYP2D6CYP2C19
SCHEMBL543786 1.00 ALDH1A1 (0.52) ALDH1A1TAAR1LMNACYP2D6CYP2C19
SCHEMBL29548275 0.88 ALDH1A1 (0.46) ALDH1A1TAAR1LMNACYP2D6CYP2C19
SCHEMBL3900092 0.87 ALDH1A1 (0.56) ALDH1A1TAAR1LMNACYP2D6CYP2C19
SCHEMBL3900089 0.87 ALDH1A1 (0.56) ALDH1A1TAAR1LMNACYP2D6CYP2C19
SCHEMBL10578482 0.85 ALDH1A1 (0.59) ALDH1A1TAAR1LMNACYP2D6CYP2C19
SCHEMBL10578491 0.85 ALDH1A1 (0.59) ALDH1A1TAAR1LMNACYP2D6CYP2C19
SCHEMBL10934483 0.85 PRMT1 (0.55) ALDH1A1TAAR1LMNA
SCHEMBL10934479 0.85 PRMT1 (0.55) ALDH1A1TAAR1LMNA
SCHEMBL24686717 0.84 PRMT1 (0.59) ALDH1A1TAAR1LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4076364-A2 NONIONIC POLYMERIC FATTY ACID COMPOUNDS FOR THE TREATMENT OF FIBROUS AMINO ACID-BASED SUBSTRATES, ESPECIALLY HAIR Momentive Performance Materials GmbH (DE) 2022-10-26 EP claimed
CN-114980854-A Non-ionic polymeric fatty acid compounds for treating fibrous substrates based on amino acids, in particular hair 迈图高新材料有限责任公司 2022-08-30 CN claimed
EP-3891204-A1 POLYCARBOXYLIC ACID COMPOUNDS FOR THE TREATMENT OF FIBROUS AMINO ACID BASED SUBSTRATES, ESPECIALLY HAIR Momentive Performance Materials Inc. (US) 2021-10-13 EP claimed
EP-3890695-A1 USE OF POLYCARBOXYLIC ACID COMPOUNDS FOR THE TREATMENT OF FIBROUS AMINO ACID BASED SUBSTRATES, ESPECIALLY HAIR Momentive Performance Materials Inc. (US) 2021-10-13 EP claimed
US-11090255-B2 Use of polycarboxylic acid compounds for the treatment of fibrious amino acid based substrates, especially hair MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2021-08-17 US claimed
CN-113164357-A Use of polycarboxylic acid compounds for treating fibrous substrates based on amino acids, in particular hair 迈图高新材料公司 2021-07-23 CN claimed
CN-113166370-A Polycarboxylic acid compounds for treating fibrous substrates based on amino acids, especially hair 迈图高新材料公司 2021-07-23 CN claimed
WO-2020117516-A1 USE OF POLYCARBOXYLIC ACID COMPOUNDS FOR THE TREATMENT OF FIBROUS AMINO ACID BASED SUBSTRATES, ESPECIALLY HAIR MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2020-06-11 WO claimed
WO-2020117509-A1 POLYCARBOXYLIC ACID COMPOUNDS FOR THE TREATMENT OF FIBROUS AMINO ACID BASED SUBSTRATES, ESPECIALLY HAIR MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2020-06-11 WO claimed
US-20200170923-A1 USE OF POLYCARBOXYLIC ACID COMPOUNDS FOR THE TREATMENT OF FIBRIOUS AMINO ACID BASED SUBSTRATES, ESPECIALLY HAIR MOMENTIVE PERFORMANCE MATERIALS INC. 2020-06-04 US claimed
EP-3891204-B1 POLYCARBOXYLIC ACID COMPOUNDS FOR THE TREATMENT OF FIBROUS AMINO ACID BASED SUBSTRATES, ESPECIALLY HAIR MOMENTIVE PERFORMANCE MAT INC (US) 2025-04-09 EP disclosed
CN-113164357-B Use of polycarboxylic acid compounds for treating fibrous substrates based on amino acids, in particular hair 迈图高新材料公司 2024-12-10 CN disclosed
CN-113166370-B Polycarboxylic acid compounds for treating fibrous substrates based on amino acids, in particular hair 迈图高新材料公司 2024-11-15 CN disclosed
US-20230102191-A1 NONIONIC POLYMERIC FATTY ACID COMPOUNDS FOR THE TREATMENT OF FIBROUS AMINO ACID-BASED SUBSTRATES, ESPECIALLY HAIR MOMENTIVE PERFORMANCE MAT GMBH (DE) 2023-03-30 US disclosed
EP-4076364-A2 NONIONIC POLYMERIC FATTY ACID COMPOUNDS FOR THE TREATMENT OF FIBROUS AMINO ACID-BASED SUBSTRATES, ESPECIALLY HAIR Momentive Performance Materials GmbH (DE) 2022-10-26 EP disclosed
WO-2020117516-A1 USE OF POLYCARBOXYLIC ACID COMPOUNDS FOR THE TREATMENT OF FIBROUS AMINO ACID BASED SUBSTRATES, ESPECIALLY HAIR MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2020-06-11 WO disclosed
WO-2020117516-A1 USE OF POLYCARBOXYLIC ACID COMPOUNDS FOR THE TREATMENT OF FIBROUS AMINO ACID BASED SUBSTRATES, ESPECIALLY HAIR MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2020-06-11 WO disclosed
US-20200170923-A1 USE OF POLYCARBOXYLIC ACID COMPOUNDS FOR THE TREATMENT OF FIBRIOUS AMINO ACID BASED SUBSTRATES, ESPECIALLY HAIR MOMENTIVE PERFORMANCE MATERIALS INC. 2020-06-04 US disclosed
US-20200170923-A1 USE OF POLYCARBOXYLIC ACID COMPOUNDS FOR THE TREATMENT OF FIBRIOUS AMINO ACID BASED SUBSTRATES, ESPECIALLY HAIR MOMENTIVE PERFORMANCE MATERIALS INC. 2020-06-04 US disclosed
US-10617617-B1 Polycarboxylic acid compounds for the treatment of fibrious amino acid based substrates, especially hair MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2020-04-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10617617-B1 Polycarboxylic acid compounds for the treatment of fibrious amino acid based substrates, especially hair ABAT, PCCA, FAH ALDH1A1 820/4885TAAR1 2014/4885LMNA 2442/4885
US-20230102191-A1 NONIONIC POLYMERIC FATTY ACID COMPOUNDS FOR THE TREATMENT OF FIBROUS AMINO ACID-BASED SUBSTRATES, ESPECIALLY HAIR ELOVL3, ELOVL1, FIBP ALDH1A1 1548/4885TAAR1 1301/4885LMNA 1310/4885
US-11090255-B2 Use of polycarboxylic acid compounds for the treatment of fibrious amino acid based substrates, especially hair ABAT, PCCA, FH ALDH1A1 673/4885TAAR1 2011/4885LMNA 2225/4885
US-20200170923-A1 USE OF POLYCARBOXYLIC ACID COMPOUNDS FOR THE TREATMENT OF FIBRIOUS AMINO ACID BASED SUBSTRATES, ESPECIALLY HAIR ABAT, PCCA, FH ALDH1A1 673/4885TAAR1 2011/4885LMNA 2225/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.