SCHEMBL543785

SCHEMBL543785

O=C(O)/C=C\C(=O)NCCC(=O)O

nearest known ligand 0.52

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.52
TAAR1 Q96RJ0 6/20 0.52
LMNA P02545 2/20 0.46
CYP2D6 P10635 1/20 0.46
CYP2C19 P33261 1/20 0.46
ECE1 P42892 1/20 0.43
TSHR P16473 2/20 0.41
TP53 P04637 1/20 0.41
EGLN1 Q9GZT9 1/20 0.41
EGLN3 Q9H6Z9 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21836734 1.00 ALDH1A1 (0.52) ALDH1A1TAAR1LMNACYP2D6CYP2C19
SCHEMBL543786 1.00 ALDH1A1 (0.52) ALDH1A1TAAR1LMNACYP2D6CYP2C19
SCHEMBL29548275 0.88 ALDH1A1 (0.46) ALDH1A1TAAR1LMNACYP2D6CYP2C19
SCHEMBL3900092 0.87 ALDH1A1 (0.56) ALDH1A1TAAR1LMNACYP2D6CYP2C19
SCHEMBL3900089 0.87 ALDH1A1 (0.56) ALDH1A1TAAR1LMNACYP2D6CYP2C19
SCHEMBL10578482 0.85 ALDH1A1 (0.59) ALDH1A1TAAR1LMNACYP2D6CYP2C19
SCHEMBL10578491 0.85 ALDH1A1 (0.59) ALDH1A1TAAR1LMNACYP2D6CYP2C19
SCHEMBL10934483 0.85 PRMT1 (0.55) ALDH1A1TAAR1LMNA
SCHEMBL10934479 0.85 PRMT1 (0.55) ALDH1A1TAAR1LMNA
SCHEMBL24686717 0.84 PRMT1 (0.59) ALDH1A1TAAR1LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0080451-B1 METHOD AND COMPOSITION FOR DIENE RUBBER TREATMENT MONSANTO COMPANY (US) 1985-09-18 EP claimed
EP-0080451-A1 Method and composition for diene rubber treatment MONSANTO COMPANY (US) 1983-06-01 EP claimed
US-20260007757-A1 ANTIBODY-RECRUITING MOLECULES ABLYNX NV (BE) 2026-01-08 US disclosed
WO-2025262150-A2 ANTIBODY-RECRUITING MOLECULES ABLYNX NV (BE) 2025-12-26 WO disclosed
EP-4638489-A1 PROTEIN-BASED CONJUGATION CARRIERS Ablynx N.V. (BE) 2025-10-29 EP disclosed
US-20240415974-A1 PROTEIN-BASED CONJUGATION CARRIERS ABLYNX N.V. (BE) 2024-12-19 US disclosed
CN-113164357-B Use of polycarboxylic acid compounds for treating fibrous substrates based on amino acids, in particular hair 迈图高新材料公司 2024-12-10 CN disclosed
CN-113166370-B Polycarboxylic acid compounds for treating fibrous substrates based on amino acids, in particular hair 迈图高新材料公司 2024-11-15 CN disclosed
WO-2024146920-A1 DRUG CONJUGATES FOR THE TREATMENT OF OCULAR DISORDERS ASCENDIS PHARMA OPHTHALMOLOGY DIVISION A/S (DK) 2024-07-11 WO disclosed
WO-2024146902-A1 METHODS OF PRODUCING HYDROGEL MICROSPHERES ASCENDIS PHARMA A/S (DK) 2024-07-11 WO disclosed
WO-2024133935-A1 PROTEIN-BASED CONJUGATION CARRIERS ABLYNX NV (BE) 2024-06-27 WO disclosed
EP-1435375-A1 RUBBER COMPOSITION Bridgestone Corporation (JP) 2004-07-07 EP disclosed
EP-0265818-B1 Process for the preparation of N,N-disubstituted beta-aminoacids and their use in water-proofing leather and skins STOCKHAUSEN CHEM FAB GMBH (DE) 1994-09-28 EP disclosed
EP-0265818-A2 Process for the preparation of N,N-disubstituted beta-aminoacids and their use in water-proofing leather and skins Chemische Fabrik Stockhausen GmbH (DE) 1988-05-04 EP disclosed
EP-0080451-B1 METHOD AND COMPOSITION FOR DIENE RUBBER TREATMENT MONSANTO COMPANY (US) 1985-09-18 EP disclosed
US-4433114-A SULFUR OR ORGANOSULFUR COMPOUNDS, MALEAMIC ACID OR DERIVATIVES, TACKINESS, GREEN STRENGTH MONSANTO COMPANY (US) 1984-02-21 US disclosed
EP-0080451-A1 Method and composition for diene rubber treatment MONSANTO COMPANY (US) 1983-06-01 EP disclosed
US-4374956-A METAL ADHESIVES MONSANTO COMPANY (US) 1983-02-22 US disclosed
US-4350740-A SUBSTITUTED MALEAMIC ACID MODIFIER; ADHESION TO METALS MONSANTO COMPANY (US) 1982-09-21 US disclosed
US-4320173-A REINFORCEMENT AND ADHESIVES FOR VULCANIZED PRODUCTS MONSANTO COMPANY (US) 1982-03-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260007757-A1 ANTIBODY-RECRUITING MOLECULES FCGR3B, FCGR2A, FCGR1A ALDH1A1 3892/4885TAAR1 4532/4885LMNA 3166/4885
US-20240415974-A1 PROTEIN-BASED CONJUGATION CARRIERS HSPBP1, STAMBP, CRYAB ALDH1A1 3243/4885TAAR1 3731/4885LMNA 3347/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.