Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.31 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | CSF1R | P07333 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21837303 | 0.88 | GPR119 (0.32) | PRMT6GPR119PDPK1BRD4ADORA1 | |
| SCHEMBL21837304 | 0.86 | ADORA3 (0.36) | BRD4SMN1; SMN2ADORA1 | |
| SCHEMBL17465432 | 0.85 | BRD4 (0.35) | PRMT6PDPK1BRD4KDM4EALDH1A1 | |
| SCHEMBL17465396 | 0.84 | LGALS9 (0.38) | PDPK1BRD4ADORA1 | |
| SCHEMBL17479346 | 0.84 | LGALS9 (0.38) | PDPK1BRD4ADORA1 | |
| SCHEMBL21837309 | 0.82 | GPR119 (0.32) | GPR119PDPK1BRD4KDM4EALDH1A1 | |
| SCHEMBL17453456 | 0.80 | RPS6KB1 (0.31) | GPR119PDPK1 | |
| SCHEMBL17465435 | 0.80 | BRD4 (0.35) | PRMT6PDPK1BRD4KDM4EALDH1A1 | |
| SCHEMBL17465397 | 0.80 | SMN1; SMN2 (0.35) | PRMT6PDPK1BRD4KDM4EALDH1A1 | |
| SCHEMBL21837302 | 0.79 | GPR119 (0.31) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4023650-A1 | 4'-SUBSTITUTED-FURO[3,2-D]PYRIMIDINE AND -PYRROLO[3,2- D]PYRIMIDINE DERIVATIVES USEFUL FOR TREATING RESPIRATORY SYNCITIAL VIRUS INFECTIONS | Gilead Sciences, Inc. (US) | 2022-07-06 | — | — | EP | disclosed |
| EP-3693367-A1 | THIENO [3,2-D]PYRIMIDINES, FURO [3,2,D]PYRIMIDINES AND PYRROLO [3,2-D]PYRIMIDINES USEFUL FOR TREATING RESPIRATORY SYNCITIAL VIRUS INFECTIONS | Gilead Sciences, Inc. (US) | 2020-08-12 | — | — | EP | disclosed |
| EP-3174870-B1 | THIENO [3,2-D]PYRIMIDINES, FURO [3,2,D]PYRIMIDINES AND PYRROLO [3,2-D]PYRIMIDINES USEFUL FOR TREATING RESPIRATORY SYNCITIAL VIRUS INFECTIONS | GILEAD SCIENCES INC (US) | 2020-04-15 | — | — | EP | disclosed |