SCHEMBL2184378

SCHEMBL2184378

[CH2]C(=O)OC12CC3CC(CC(C3)C1C)C2

nearest known ligand 0.35

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.35
NAAA Q02083 1/20 0.34
ALDH1A1 P00352 3/20 0.33
EPHX2 P34913 5/20 0.33
NPSR1 Q6W5P4 1/20 0.32
GLA P06280 1/20 0.32
L3MBTL1 Q9Y468 2/20 0.31
SCN1A P35498 1/20 0.31
SCN2A Q99250 1/20 0.31
SCN3A Q9NY46 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
TSHR P16473 2/20 0.31
EPHX1 P07099 1/20 0.31
GAA P10253 1/20 0.30
MAPT P10636 1/20 0.30
XBP1 P17861 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27659428 0.84 NAAA (0.35) HSD17B10NAAAALDH1A1EPHX2NPSR1
SCHEMBL2812415 0.84 NAAA (0.35) HSD17B10NAAAALDH1A1EPHX2NPSR1
SCHEMBL251058 0.81 NAAA (0.32) NAAAALDH1A1EPHX2NPSR1
SCHEMBL284284 0.81 NAAA (0.32) NAAANPSR1
SCHEMBL22832087 0.81 NAAA (0.32) NAAAEPHX2NPSR1
SCHEMBL5917758 0.81 THRB (0.37) HSD17B10NAAAALDH1A1NPSR1GLA
SCHEMBL7749055 0.81 SCN1A (0.46) ALDH1A1NPSR1GLASCN1ASCN2A
Ethane SCHEMBL28205575 0.80 NAAA (0.31) NAAA
SCHEMBL6292970 0.80 TGM2 (0.33) NPSR1
SCHEMBL27673001 0.79 OPRM1 (0.36) HSD17B10NAAAALDH1A1EPHX2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110165513-A1 PHOTORESIST COMPOSITION SUMITOMO CHEMICAL COMPANY LTD (JP) 2011-07-07 US disclosed