Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6117602 | 0.98 | NPC1 (0.50) | NPC1RAB9APTPN1HTR7PLOD2 | |
| SCHEMBL106663 | 0.81 | NPC1 (0.48) | NPC1RAB9APTPN1CA1CA2 | |
| SCHEMBL685958 | 0.81 | KMT2A (0.48) | NPC1RAB9APTPN1PLOD2CES1 | |
| SCHEMBL10122613 | 0.80 | GSK3B (0.52) | NPC1RAB9ACES2CES1CA1 | |
| SCHEMBL10122612 | 0.80 | GSK3B (0.52) | NPC1RAB9ACES2CES1CA1 | |
| SCHEMBL686324 | 0.80 | GSK3B (0.50) | NPC1RAB9ACES2CES1CTNNB1 | |
| SCHEMBL98167 | 0.79 | KMT2A (0.50) | NPC1RAB9APTPN1PLOD2CES1 | |
| Bromide SCHEMBL2521756 | 0.79 | GSK3B (0.48) | NPC1RAB9ACES2CES1CTNNB1 | |
| SCHEMBL686330 | 0.79 | MMP2 (0.38) | NPC1RAB9ACA1CA2SMN1; SMN2 | |
| SCHEMBL10122618 | 0.78 | CES2 (0.50) | NPC1RAB9ACES2CES1CTNNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8524440-B2 | Photoresist composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-09-03 | — | — | US | disclosed |
| US-20110165513-A1 | PHOTORESIST COMPOSITION | SUMITOMO CHEMICAL COMPANY LTD (JP) | 2011-07-07 | — | — | US | disclosed |