SCHEMBL2184909

SCHEMBL2184909

Cc1ccc2cc(C(=O)O)cc(O)c2c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 2/20 0.59
CSNK2A1 P68400 1/20 0.47
ALDH1A1 P00352 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
KDM4E B2RXH2 2/20 0.45
CA12 O43570 2/20 0.45
CA1 P00915 2/20 0.45
CA2 P00918 2/20 0.45
MAPT P10636 2/20 0.45
CA4 P22748 2/20 0.45
CA6 P23280 2/20 0.45
CA7 P43166 2/20 0.45
CA9 Q16790 2/20 0.45
CA14 Q9ULX7 2/20 0.45
MAPK1 P28482 2/20 0.45
TPMT P51580 1/20 0.45
LMNA P02545 1/20 0.45
TP53 P04637 1/20 0.45
CA3 P07451 1/20 0.45
SELL P14151 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2186294 0.86 SLC6A2 (0.54) PRMT1CSNK2A1ALDH1A1SMN1; SMN2KDM4E
SCHEMBL1681429 0.81 PRMT1 (0.63) PRMT1ALDH1A1SMN1; SMN2KDM4ECA12
SCHEMBL22663048 0.81 ALDH1A1 (0.44) PRMT1CSNK2A1ALDH1A1SMN1; SMN2KDM4E
SCHEMBL5860632 0.81 TTR (0.46) PRMT1CSNK2A1ALDH1A1SMN1; SMN2KDM4E
SCHEMBL15006668 0.79 PRMT1 (0.59) PRMT1ALDH1A1SMN1; SMN2KDM4ECA12
SCHEMBL30220366 0.79 PRMT1 (0.59) PRMT1ALDH1A1SMN1; SMN2KDM4ECA12
SCHEMBL27619808 0.79 PRMT1 (0.59) PRMT1ALDH1A1SMN1; SMN2KDM4ECA12
SCHEMBL741721 0.79 PRMT1 (0.59) PRMT1ALDH1A1SMN1; SMN2KDM4ECA12
SCHEMBL10279934 0.79 PRMT1 (0.59) PRMT1ALDH1A1SMN1; SMN2KDM4ECA12
SCHEMBL5735509 0.79 PRMT1 (0.59) PRMT1ALDH1A1SMN1; SMN2KDM4ECA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230265066-A1 NAPHTHOPYRAN-CONTAINING COMPOUND, POLYMER, MIXTURE, COMPOSITION AND USE THEREOF IN WATER-SOLUBLE PHOTOCHROMIC MATERIALS NANO AND ADVANCED MATERIALS INSTITUTE LIMITED (HK) 2023-08-24 US disclosed
WO-2023287067-A1 ANTIBACTERIAL COMPOUND 주식회사 엘지화학 2023-01-19 WO disclosed
EP-2343279-B1 FUSED-RING DERIVATIVE AND MEDICAL APPLICATION OF SAME KISSEI PHARMACEUTICAL (JP) 2018-02-28 EP disclosed
US-9745336-B2 Fluorescent dye compounds, conjugates and uses thereof APPLIED BIOSYSTEMS, LLC (US) 2017-08-29 US disclosed
US-20140303003-A1 Fluorescent Dye Compounds, Conjugates and Uses Thereof APPLIED BIOSYSTEMS, LLC (US) 2014-10-09 US disclosed
US-8729267-B2 Fluorescent dye compounds, conjugates and uses thereof APPLIED BIOSYSTEMS, LLC (US) 2014-05-20 US disclosed
CN-102186824-B Fused-ring derivative and medical application of same KISSEI PHARMACEUTICAL 2014-03-12 CN disclosed
US-8263622-B2 Fused-ring derivative and medical application of same KISSEI PHARMACEUTICAL CO., LTD. (JP) 2012-09-11 US disclosed
US-20110250699-A1 Fluorescent Dye Compounds, Conjugates and Uses Thereof Life Technologies Corporation (US) 2011-10-13 US disclosed
CN-102186824-A Fused-ring derivative and medical application of same KISSEI PHARMACEUTICAL 2011-09-14 CN disclosed
US-20110207935-A1 FUSED-RING DERIVATIVE AND MEDICAL APPLICATION OF SAME KISSEI PHARMACEUTICAL CO., LTD. (JP) 2011-08-25 US disclosed
EP-2343279-A1 FUSED-RING DERIVATIVE AND MEDICAL APPLICATION OF SAME Kissei Pharmaceutical Co., Ltd. (JP) 2011-07-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230265066-A1 NAPHTHOPYRAN-CONTAINING COMPOUND, POLYMER, MIXTURE, COMPOSITION AND USE THEREOF IN WATER-SOLUBLE PHOTOCHROMIC MATERIALS TYR, PWWP2B, GANC PRMT1 4679/4885CSNK2A1 1396/4885ALDH1A1 3291/4885
US-20110207935-A1 FUSED-RING DERIVATIVE AND MEDICAL APPLICATION OF SAME XDH, OAT, PON1 PRMT1 1250/4885CSNK2A1 3829/4885ALDH1A1 185/4885
US-20110250699-A1 Fluorescent Dye Compounds, Conjugates and Uses Thereof GFPT1, SLC46A1, SLC7A5 PRMT1 2119/4885CSNK2A1 4701/4885ALDH1A1 146/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.