Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 11/20 | 0.51 |
| ▸ | CDK9 | P50750 | 11/20 | 0.51 |
| ▸ | CDK4 | P11802 | 2/20 | 0.51 |
| ▸ | CCND1 | P24385 | 2/20 | 0.51 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.51 |
| ▸ | CDK2 | P24941 | 1/20 | 0.51 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.51 |
| ▸ | CDK3 | Q00526 | 1/20 | 0.51 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | CBLB | Q13191 | 1/20 | 0.37 |
| ▸ | KCNN3 | Q9UGI6 | 3/20 | 0.35 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.35 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.35 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.35 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.35 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.35 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17690933 | 0.81 | PRKAB2 (0.49) | CCNT1CDK9CDK4CCND1CCNE1 | |
| SCHEMBL17690983 | 0.77 | PDE10A (0.38) | CCNT1CDK9CDK4CCND1CCNE1 | |
| SCHEMBL25807858 | 0.75 | CCNT1 (0.54) | CCNT1CDK9CDK4CCND1CCNE1 | |
| SCHEMBL11605754 | 0.74 | CCNT1 (0.40) | CCNT1CDK9CDK4CCND1CCNE1 | |
| SCHEMBL3460690 | 0.73 | PIK3CG (0.48) | PDE10A | |
| SCHEMBL14545195 | 0.73 | CCNT1 (0.52) | CCNT1CDK9CDK4CCND1CCNE1 | |
| SCHEMBL24408207 | 0.71 | PRKAB2 (0.46) | CCNT1CDK9CDK4CCND1CCNE1 | |
| SCHEMBL24418622 | 0.71 | CCNT1 (0.51) | CCNT1CDK9CDK4CCND1CCNE1 | |
| SCHEMBL29344715 | 0.70 | PDE10A (0.67) | CCNT1CDK9PDE10AKCNN3 | |
| SCHEMBL20664459 | 0.70 | PDE10A (0.43) | CCNT1CDK9CCNE1CDK2PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200102311-A1 | Monoacylglycerol Lipase Modulators | JANSSEN PHARMACEUTICA NV (BE) | 2020-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200102311-A1 | Monoacylglycerol Lipase Modulators | MGLL, LPL, PNLIP | CCNT1 3977/4885CDK9 1996/4885CDK4 2404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.