Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GRN | P28799 | 1/20 | 0.40 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | BRS3 | P32247 | 2/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21851483 | 0.82 | LMNA (0.46) | LMNAKMT2AGRNSORT1KDM4E | |
| SCHEMBL21849206 | 0.76 | KDM4E (0.44) | LMNAKMT2AKDM4EALDH1A1BRS3 | |
| SCHEMBL13990481 | 0.76 | LMNA (0.53) | LMNAKMT2AGRNSORT1KDM4E | |
| SCHEMBL21645117 | 0.70 | KDM4E (0.44) | LMNAKMT2AKDM4EALDH1A1MEN1 | |
| SCHEMBL19954279 | 0.70 | LMNA (0.53) | LMNAKMT2AKDM4EALDH1A1RXFP1 | |
| SCHEMBL29696309 | 0.70 | LMNA (0.53) | LMNAKMT2AKDM4EALDH1A1RXFP1 | |
| SCHEMBL23478708 | 0.69 | KIF11 (0.46) | — | |
| SCHEMBL19592843 | 0.68 | NOTUM (0.49) | KMT2AKDM4EALDH1A1BRS3NLRP3 | |
| SCHEMBL46317 | 0.65 | KDM4E (0.58) | LMNAKMT2AGRNSORT1KDM4E | |
| SCHEMBL31516755 | 0.65 | KDM4E (0.58) | LMNAKMT2AGRNSORT1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200102311-A1 | Monoacylglycerol Lipase Modulators | JANSSEN PHARMACEUTICA NV (BE) | 2020-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200102311-A1 | Monoacylglycerol Lipase Modulators | MGLL, LPL, PNLIP | LMNA 1845/4885KMT2A 2234/4885GRN 2285/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.