SCHEMBL4965733

SCHEMBL4965733

CCC(=O)OC(C)Cc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.53
CTSK P43235 2/20 0.49
CTSL P07711 1/20 0.49
CTSB P07858 1/20 0.49
CTSH P09668 1/20 0.49
NPC1 O15118 1/20 0.49
RAB9A P51151 1/20 0.49
CYP1A2 P05177 1/20 0.47
TRPA1 O75762 2/20 0.46
ACE P12821 1/20 0.45
SRR Q9GZT4 1/20 0.44
ALPI P09923 1/20 0.44
PKM P14618 1/20 0.44
PTGS1 P23219 1/20 0.44
XIAP P98170 1/20 0.44
SLC7A5 Q01650 1/20 0.44
PPARG P37231 1/20 0.44
PPARA Q07869 1/20 0.44
MMP8 P22894 1/20 0.44
TAAR1 Q96RJ0 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27484932 0.96 CTSK (0.50) TSHRCTSKCTSLCTSBCTSH
SCHEMBL22474253 0.90 SRR (0.50) ACESRRPPARGPPARA
SCHEMBL9696685 0.87 TSHR (0.55) TSHRCTSKCTSLCTSBCTSH
SCHEMBL21850321 0.86 TSHR (0.44) TSHRCTSKCTSLCTSBCTSH
SCHEMBL21850359 0.86 TSHR (0.44) TSHRCTSKCTSLCTSBCTSH
SCHEMBL22474214 0.86 MME (0.49) TSHRCTSKCTSLCTSBACE
SCHEMBL4223740 0.86 CTSK (0.50) TSHRCTSKCTSLCTSBCTSH
SCHEMBL19932800 0.86 ALOX15 (0.44) TSHRPTGS1PPARGPPARA
SCHEMBL10333475 0.86 CTSK (0.50) TSHRCTSKCTSLCTSBCTSH
SCHEMBL21850411 0.84 TSHR (0.49) TSHRNPC1RAB9ACYP1A2TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117480236-A Perfume for improving state of agitation and evaluation method 奇华顿股份有限公司 2024-01-30 CN claimed
US-20030036489-A1 Consumable composition comprising perfumed particles and article containing the same THE PROCTER & GAMBLE COMPANY 2003-02-20 US claimed
WO-2002090481-A1 COMPOSITIONS AND ARTICLES FOR EFFECTIVE DEPOSITION OF PERFUME THE PROCTER & GAMBLE COMPANY (US) 2002-11-14 WO claimed
EP-3506754-B1 PICOLINAMIDE N-OXIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY CORTEVA AGRISCIENCE LLC (US) 2023-08-09 EP disclosed
EP-3255991-B1 PICOLINAMIDES AS FUNGICIDES DOW AGROSCIENCES LLC (US) 2020-09-30 EP disclosed
EP-3240408-B1 PICOLINAMIDES WITH FUNGICIDAL ACTIVITY DOW AGROSCIENCES LLC (US) 2020-04-08 EP disclosed
WO-2019173665-A1 PICOLINAMIDES AS FUNGICIDES DOW AGROSCIENCES LLC (US) 2019-09-12 WO disclosed
WO-2018045000-A1 PICOLINAMIDES AS FUNGICIDES DOW AGROSCIENCES LLC (US) 2018-03-08 WO disclosed
WO-2018044996-A1 PICOLINAMIDES AS FUNGICIDES DOW AGROSCIENCES LLC (US) 2018-03-08 WO disclosed
US-20080207476-A1 PARTICLES CONTAINING PERFUME HAVING IMPROVED FRAGRANCE PROPERTIES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2008-08-28 US disclosed
WO-2007128326-A1 PERFUME DELIVERY SYSTEM FOR CLEANERS EVONIK GOLDSCHMIDT GMBH (DE) 2007-11-15 WO disclosed
WO-2003086371-A2 USE OF EP4 RECEPTOR LIGANDS IN THE TREATMENT OF IL-6 INVOLVED DISEASES PFIZER JAPAN INC. (JP) 2003-10-23 WO disclosed
US-20030024997-A1 Air freshening compositions, articles comprising same and methods THE PROCTER & GAMBLE COMPANY 2003-02-06 US disclosed
US-20030013632-A1 Dryer-added fabric softening articles and methods THE PROCTER & GAMBLE COMPANY 2003-01-16 US disclosed
WO-2002089862-A2 AIR FRESHENING COMPOSITIONS, ARTICLES COMPRISING SAME AND METHODS FOR PREPARING SAME THE PROCTER & GAMBLE COMPANY (US) 2002-11-14 WO disclosed
WO-2002090479-A1 PERFUMED PARTICLES AND ARTICLES CONTAINING THE SAME THE PROCTER & GAMBLE COMPANY (US) 2002-11-14 WO disclosed
EP-0808358-A4 PERFUMED BLEACHING COMPOSITIONS PROCTER & GAMBLE (US) 1999-08-11 EP disclosed
EP-0808358-A1 PERFUMED BLEACHING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1997-11-26 EP disclosed
EP-0778342-A1 Detergent compositions THE PROCTER & GAMBLE COMPANY (US) 1997-06-11 EP disclosed
WO-1996019560-A1 PERFUMED BLEACHING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1996-06-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030024997-A1 Air freshening compositions, articles comprising same and methods PIEZO1, TMEM63A, KIT TSHR 4670/4885CTSK 1141/4885CTSL 918/4885
US-20080207476-A1 PARTICLES CONTAINING PERFUME HAVING IMPROVED FRAGRANCE PROPERTIES DSC1, DSG1, PIEZO1 TSHR 4659/4885CTSK 1046/4885CTSL 3040/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.