Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.46 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | PTK2B | Q14289 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20570896 | 0.87 | MAPT (0.47) | NCF1SLC22A12ELANEMAPTKDM4E | |
| SCHEMBL7053633 | 0.79 | NCF1 (0.50) | NCF1SLC22A12LOXL2HTR1AADRA1D | |
| SCHEMBL6248338 | 0.76 | NCF1 (0.47) | NCF1SLC22A12LOXL2HTR1AADRA1D | |
| SCHEMBL21082253 | 0.75 | NCF1 (0.50) | NCF1SLC22A12LOXL2HTR1AADRA1D | |
| SCHEMBL2816694 | 0.74 | LOXL2 (0.47) | NCF1SLC22A12LOXL2ELANEHTR1A | |
| SCHEMBL13601938 | 0.72 | HTR1A (0.43) | NCF1SLC22A12LOXL2HTR1AADRA1D | |
| SCHEMBL826018 | 0.71 | NCF1 (0.50) | NCF1LOXL2HTR1AADRA1DADRA1A | |
| SCHEMBL2333890 | 0.69 | HTR1A (0.47) | NCF1SLC22A12LOXL2HTR1AADRA1D | |
| SCHEMBL8908139 | 0.69 | HTR1A (0.47) | NCF1SLC22A12LOXL2HTR1AADRA1D | |
| SCHEMBL2116696 | 0.68 | IFNAR1 (0.43) | ELANEMAPTCYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020072656-A1 | IMIDOZOPYRIMIDINE DERIVATIVES | GILEAD SCIENCES, INC. (US) | 2020-04-09 | — | — | WO | disclosed |