SCHEMBL826018

SCHEMBL826018

CC(C)c1ccnc2ccccc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NCF1 P14598 1/20 0.50
LOXL2 Q9Y4K0 1/20 0.47
HTR1A P08908 2/20 0.44
ADRA1D P25100 2/20 0.44
ADRA1A P35348 2/20 0.44
ADRA1B P35368 2/20 0.44
MAPT P10636 4/20 0.43
KDM4E B2RXH2 2/20 0.43
CYP1A2 P05177 3/20 0.40
CYP3A4 P08684 3/20 0.40
ALDH1A1 P00352 2/20 0.40
CYP2C9 P11712 2/20 0.40
CYP2C19 P33261 2/20 0.40
HSD17B10 Q99714 2/20 0.40
CYP2D6 P10635 2/20 0.40
HIF1A Q16665 2/20 0.40
AAK1 Q2M2I8 1/20 0.40
NPC1 O15118 2/20 0.40
TP53 P04637 2/20 0.40
RAB9A P51151 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrazine SCHEMBL27892138 0.96 NCF1 (0.52) NCF1LOXL2HTR1AADRA1DADRA1A
SCHEMBL84436 0.86 MAPT (0.52) NCF1HTR1AMAPTKDM4ECYP1A2
SCHEMBL30994907 0.86 MAPT (0.52) NCF1HTR1AMAPTKDM4ECYP1A2
SCHEMBL1496289 0.84 NCF1 (0.47) NCF1LOXL2HTR1AADRA1DADRA1A
SCHEMBL264120 0.84 NCF1 (0.52) NCF1LOXL2HTR1AADRA1DADRA1A
SCHEMBL14120837 0.84 NCF1 (0.52) NCF1LOXL2HTR1AADRA1DADRA1A
SCHEMBL9576579 0.84 NCF1 (0.47) NCF1LOXL2HTR1AADRA1DADRA1A
SCHEMBL1496311 0.84 NCF1 (0.47) NCF1LOXL2HTR1AADRA1DADRA1A
SCHEMBL14122720 0.84 NCF1 (0.52) NCF1LOXL2HTR1AADRA1DADRA1A
SCHEMBL14431011 0.84 NCF1 (0.47) NCF1LOXL2HTR1AADRA1DADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 623 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118931996-A Method for preparing high-purity glucopentasaccharide 山东国力生物科技有限公司 2024-11-12 CN claimed
CN-112939857-A Synthetic method of alkylated quinoline compound 中国科学院大连化学物理研究所 2021-06-11 CN claimed
US-20250186646-A1 Use of Volatile Compositions to Limit or Eliminate Perception of Fecal Malodour FIRMENICH SA (CH) 2025-06-12 US disclosed
CN-119562995-A Polysiloxane-based intumescent coating composition 汉伯公司 2025-03-04 CN disclosed
WO-2025036155-A1 PREPARATION METHOD FOR AND USE OF FUCOSE AND INTERMEDIATE THEREOF 北京国科星联科技有限公司 2025-02-20 WO disclosed
EP-4218837-B1 VOLATILE COMPOSITIONS TO LIMIT OR ELIMINATE PERCEPTION OF FECAL MALODOUR FIRMENICH & CIE (CH) 2024-11-27 EP disclosed
CN-118931996-A Method for preparing high-purity glucopentasaccharide 山东国力生物科技有限公司 2024-11-12 CN disclosed
US-20240301319-A1 PERFUMING COMPOSITIONS FIRMNICH SA (CH) 2024-09-12 US disclosed
US-20240239811-A1 5-(5-(PIPERIDIN-4-YL)THIENO[3,2-C]PYRAZOL-2-YL]INDAZOLE DERIVATIVES AND RELATED COMPOUNDS AS MODULATORS FOR SPLICING NUCLEIC ACIDS AND FOR THE T REMIX THERAPEUTICS INC. 2024-07-18 US disclosed
US-12030878-B2 Substituted indole ether compounds BRISTOL-MYERS SQUIBB COMPANY (US) 2024-07-09 US disclosed
US-12030878-B2 Substituted indole ether compounds BRISTOL-MYERS SQUIBB COMPANY (US) 2024-07-09 US disclosed
US-7220735-B2 Benzimidazolone histamine H3 antagonists SCHERING CORPORATION (US) 2007-05-22 US disclosed
US-7189728-B2 Inhibitors of dipeptidyl peptidase IV FERRING, BV (NL) 2007-03-13 US disclosed
US-20070021351-A1 Liver/plasma concentration ratio for dosing hepatitis C virus protease inhibitor SCHERING CORPORATION 2007-01-25 US disclosed
US-20070010431-A1 Pharmaceutical formulations and methods of treatment using the same SCHERING CORPORATION 2007-01-11 US disclosed
US-20070004635-A1 Method of treating interferon non-responders using HCV protease inhibitor SCHERING CORPORATION 2007-01-04 US disclosed
WO-2006007700-A1 HEPATITIS C INHIBITOR DIPEPTIDE ANALOGS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2006-01-26 WO disclosed
WO-2006000085-A1 HEPATITIS C INHIBITOR PEPTIDE ANALOGS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2006-01-05 WO disclosed
US-20050148775-A1 Process for production of heteroaryl-type boron compounds with iridium catalyst MITSUBISHI RAYON CO., LTD. (JP) 2005-07-07 US disclosed
EP-1481978-A1 PROCESS FOR PRODUCTION OF HETEROARYL-TYPE BORON COMPOUNDS WITH IRIDIUM CATALYST Mitsubishi Rayon Co., Ltd. (JP) 2004-12-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070004635-A1 Method of treating interferon non-responders using HCV protease inhibitor IFNAR1, IFNG, IRF3 NCF1 964/4885LOXL2 2182/4885HTR1A 2998/4885
US-20050148775-A1 Process for production of heteroaryl-type boron compounds with iridium catalyst PIN4, IPO5, HLCS NCF1 1088/4885LOXL2 3016/4885HTR1A 4327/4885
US-20070021351-A1 Liver/plasma concentration ratio for dosing hepatitis C virus protease inhibitor PYGL, SERPINB1, PREP NCF1 561/4885LOXL2 1198/4885HTR1A 3816/4885
US-20070010431-A1 Pharmaceutical formulations and methods of treatment using the same LPXN, SLC5A11, F12 NCF1 2735/4885LOXL2 2232/4885HTR1A 2302/4885
US-12030878-B2 Substituted indole ether compounds TLR7, TLR8, TLR1 NCF1 252/4885LOXL2 2212/4885HTR1A 105/4885
US-20240239811-A1 5-(5-(PIPERIDIN-4-YL)THIENO[3,2-C]PYRAZOL-2-YL]INDAZOLE DERIVATIVES AND RELATED COMPOUNDS AS MODULATORS FOR SPLICING NUCLEIC ACIDS AND FOR THE T HNRNPAB, HNRNPC, HNRNPA1 NCF1 3088/4885LOXL2 3270/4885HTR1A 1226/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.