Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CCR6 | P51684 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10999510 | 0.80 | RAB9A (0.51) | KDM4EMAPTL3MBTL1ATMSMN1; SMN2 | |
| SCHEMBL2185352 | 0.80 | ALDH1A1 (0.41) | ALOX5KDM4EMAPTL3MBTL1ATM | |
| SCHEMBL2184826 | 0.75 | CDC7 (0.58) | KDM4EMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL11398132 | 0.73 | HPGD (0.43) | KDM4EMAPTL3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL11387968 | 0.73 | ALPL (0.56) | ALOX5KDM4EMAPTSMN1; SMN2NPC1 | |
| SCHEMBL12614775 | 0.73 | ALDH1A1 (0.57) | KDM4EMAPTL3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL25351222 | 0.72 | LMNA (0.53) | KDM4EL3MBTL1NPC1RAB9AKMT2A | |
| SCHEMBL1566612 | 0.72 | MAPT (0.57) | KDM4EMAPTL3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL2114584 | 0.71 | CDC7 (0.44) | KDM4EMAPTL3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL8605237 | 0.71 | HPGD (0.53) | ALOX5KDM4EL3MBTL1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2343279-B1 | FUSED-RING DERIVATIVE AND MEDICAL APPLICATION OF SAME | KISSEI PHARMACEUTICAL (JP) | 2018-02-28 | — | — | EP | disclosed |
| US-8263622-B2 | Fused-ring derivative and medical application of same | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2012-09-11 | — | — | US | disclosed |
| US-20110207935-A1 | FUSED-RING DERIVATIVE AND MEDICAL APPLICATION OF SAME | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2011-08-25 | — | — | US | disclosed |
| EP-2343279-A1 | FUSED-RING DERIVATIVE AND MEDICAL APPLICATION OF SAME | Kissei Pharmaceutical Co., Ltd. (JP) | 2011-07-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110207935-A1 | FUSED-RING DERIVATIVE AND MEDICAL APPLICATION OF SAME | XDH, OAT, PON1 | ALOX5 493/4885KDM4E 3834/4885MAPT 4366/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.