SCHEMBL2185607

SCHEMBL2185607

Cc1cc(N)c2c(c1Nc1ccccc1)C1(OC2=O)c2ccccc2Oc2ccccc21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.41
HPGD P15428 2/20 0.41
ALOX12 P18054 2/20 0.41
ALOX15 P16050 2/20 0.41
CYP2C9 P11712 1/20 0.41
BRCA1 P38398 1/20 0.41
HSD17B10 Q99714 1/20 0.41
FTO Q9C0B1 7/20 0.34
MAPT P10636 3/20 0.34
MEN1 O00255 2/20 0.34
HTT P42858 2/20 0.34
KMT2A Q03164 2/20 0.34
CYP2C19 P33261 1/20 0.34
RECQL P46063 1/20 0.34
BLM P54132 1/20 0.34
SMAD3 P84022 1/20 0.34
PRMT1 Q99873 1/20 0.34
ACE2 Q9BYF1 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
CXCR2 P25025 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4659426 0.87 ALOX15 (0.41) ALDH1A1HPGDALOX12ALOX15CYP2C9
SCHEMBL6537056 0.86 HPGD (0.40) ALDH1A1HPGDALOX12ALOX15CYP2C9
SCHEMBL10885589 0.86 HPGD (0.40) ALDH1A1HPGDALOX12ALOX15CYP2C9
SCHEMBL4667092 0.85 CYP2C9 (0.39) ALDH1A1HPGDALOX12ALOX15CYP2C9
SCHEMBL11003355 0.84 HPGD (0.39) ALDH1A1HPGDALOX12ALOX15CYP2C9
SCHEMBL9565549 0.83 HPGD (0.38) ALDH1A1HPGDALOX12ALOX15CYP2C9
SCHEMBL6535277 0.83 ALDH1A1 (0.38) ALDH1A1HPGDALOX12ALOX15CYP2C9
SCHEMBL6438083 0.81 HPGD (0.39) ALDH1A1HPGDALOX12ALOX15CYP2C9
SCHEMBL3877302 0.81 ALDH1A1 (0.37) ALDH1A1HPGDALOX12ALOX15CYP2C9
SCHEMBL8505128 0.81 ALDH1A1 (0.39) ALDH1A1HPGDALOX12ALOX15CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-5162453-A None JP disclosed
JP-10203024-A None JP disclosed
JP-10203023-A None JP disclosed
CN-117957123-A Thermosensitive recording medium 王子控股株式会社 2024-04-30 CN disclosed
CN-117659762-A High-sensitivity heat-and-humidity-resistant thermosensitive microcapsule dispersion liquid, preparation method and thermosensitive film 南阳柯丽尔科技有限公司 2024-03-08 CN disclosed
CN-116490375-A Thermosensitive recording medium 王子控股株式会社 2023-07-25 CN disclosed
CN-116200962-A Dispersing agent, coating liquid composition, and thermosensitive recording medium 星光PMC株式会社 2023-06-02 CN disclosed
CN-116034037-A Thermosensitive recording medium 王子控股株式会社 2023-04-28 CN disclosed
CN-112334319-B Heat-sensitive recording material 王子控股株式会社 2023-02-10 CN disclosed
CN-115515796-A Thermosensitive recording medium 王子控股株式会社 2022-12-23 CN disclosed
WO-2006108745-A1 COATING COMPOSITIONS FOR MARKING SUBSTRATES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2006-10-19 WO disclosed
WO-2006067073-A1 COATING COMPOSITIONS FOR MARKING SUBSTRATES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2006-06-29 WO disclosed
JP-H10203024-A HEAT SENSITIVE RECORDING MATERIAL RICOH CO LTD 1998-08-04 JP disclosed
JP-H10203023-A HEAT SENSITIVE RECORDING MATERIAL RICOH CO LTD 1998-08-04 JP disclosed
JP-H05162453-A THERMAL RECORDING MATERIAL MITSUI TOATSU CHEM INC 1993-06-29 JP disclosed
EP-0271081-B1 COLOUR DEVELOPER MATERIAL FOR PRESSURE-SENSITIVE RECORDING SHEETS, AND RECORDING SHEETS CONTAINING THIS MATERIAL JUJO PAPER CO., LTD. (JP) 1991-01-02 EP disclosed
EP-0343014-A1 Thermal record material The Wiggins Teape Group Limited (GB) 1989-11-23 EP disclosed
EP-0337426-A2 Heat sensitive recording material NEW OJI PAPER CO., LTD. (JP) 1989-10-18 EP disclosed
US-4826806-A CHROMOGENIC DYES SHIN NISSO KAKO CO., LTD. (JP) 1989-05-02 US disclosed
EP-0271081-A2 Colour developer material for pressure-sensitive recording sheets, and recording sheets containing this material JUJO PAPER CO., LTD. (JP) 1988-06-15 EP disclosed