Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11205801 | 1.00 | ALDH1A1 (0.48) | ALDH1A1MAPTCTSKSMN1; SMN2POLB | |
| SCHEMBL21870595 | 1.00 | ALDH1A1 (0.48) | ALDH1A1MAPTCTSKSMN1; SMN2POLB | |
| SCHEMBL21660824 | 0.88 | CTSK (0.39) | ALDH1A1MAPTCTSKSMN1; SMN2POLB | |
| SCHEMBL11203880 | 0.87 | SMN1; SMN2 (0.46) | ALDH1A1MAPTSMN1; SMN2POLBHTT | |
| SCHEMBL11813285 | 0.85 | ALDH1A1 (0.47) | ALDH1A1MAPTCTSKSMN1; SMN2POLB | |
| SCHEMBL4546603 | 0.83 | ALDH1A1 (0.44) | ALDH1A1MAPTCTSKSMN1; SMN2POLB | |
| SCHEMBL24909670 | 0.83 | NFE2L2 (0.37) | ALDH1A1MAPTCTSKSMN1; SMN2POLB | |
| SCHEMBL23665158 | 0.81 | CTSK (0.33) | ALDH1A1MAPTCTSK | |
| SCHEMBL21870596 | 0.81 | CTSK (0.33) | ALDH1A1MAPTCTSK | |
| SCHEMBL469045 | 0.79 | ALDH1A1 (0.52) | ALDH1A1MAPTSMN1; SMN2HTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210221796-A1 | ANTIBACTERIAL COMPOUNDS | BLACKSMITH MEDICINES, INC. | 2021-07-22 | — | — | US | disclosed |
| WO-2020061375-A1 | ANTIBACTERIAL COMPOUNDS | FORGE THERAPEUTICS, INC. (US) | 2020-03-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210221796-A1 | ANTIBACTERIAL COMPOUNDS | SPOUT1, MRPL21, NRDC | ALDH1A1 2040/4885MAPT 2641/4885CTSK 249/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.