Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23665158 | 1.00 | CTSK (0.33) | CTSKEPHX1ALDH1A1MAPTCA2 | |
| SCHEMBL21870609 | 0.89 | SMYD3 (0.33) | CTSKEPHX1CA2 | |
| SCHEMBL21870595 | 0.81 | ALDH1A1 (0.48) | CTSKALDH1A1MAPT | |
| SCHEMBL21870591 | 0.81 | ALDH1A1 (0.48) | CTSKALDH1A1MAPT | |
| SCHEMBL24010077 | 0.81 | KCNH2 (0.35) | ALDH1A1MAPT | |
| SCHEMBL11205801 | 0.81 | ALDH1A1 (0.48) | CTSKALDH1A1MAPT | |
| SCHEMBL21660824 | 0.76 | CTSK (0.39) | CTSKEPHX1ALDH1A1MAPTCA2 | |
| SCHEMBL24909670 | 0.71 | NFE2L2 (0.37) | CTSKEPHX1ALDH1A1MAPTCA2 | |
| SCHEMBL11203880 | 0.69 | SMN1; SMN2 (0.46) | ALDH1A1MAPT | |
| SCHEMBL24010075 | 0.68 | KCNH2 (0.38) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210221796-A1 | ANTIBACTERIAL COMPOUNDS | BLACKSMITH MEDICINES, INC. | 2021-07-22 | — | — | US | disclosed |
| WO-2020061375-A1 | ANTIBACTERIAL COMPOUNDS | FORGE THERAPEUTICS, INC. (US) | 2020-03-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210221796-A1 | ANTIBACTERIAL COMPOUNDS | SPOUT1, MRPL21, NRDC | CTSK 249/4885EPHX1 3871/4885ALDH1A1 2040/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.