Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS2 | Q07890 | 1/20 | 0.49 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.43 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 2/20 | 0.39 |
| ▸ | HAT1 | O14929 | 2/20 | 0.37 |
| ▸ | EP300 | Q09472 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31000695 | 1.00 | SOS2 (0.49) | SOS2BRPF1NR4A2TRIM24TRIM33 | |
| SCHEMBL20556017 | 1.00 | SOS2 (0.49) | SOS2BRPF1NR4A2TRIM24TRIM33 | |
| SCHEMBL20556081 | 0.83 | SOS2 (0.46) | SOS2BRPF1NR4A2TRIM24TRIM33 | |
| SCHEMBL31000552 | 0.83 | ALDH1A1 (0.52) | POLBRAB9AHTR2ACNR2MAPT | |
| SCHEMBL21870868 | 0.83 | SOS2 (0.46) | SOS2BRPF1NR4A2TRIM24TRIM33 | |
| SCHEMBL21870848 | 0.81 | SOS2 (0.44) | SOS2BRPF1NR4A2TRIM24TRIM33 | |
| SCHEMBL20555789 | 0.81 | SOS2 (0.44) | SOS2BRPF1NR4A2TRIM24TRIM33 | |
| SCHEMBL17746917 | 0.79 | BRPF1 (0.50) | SOS2BRPF1NR4A2TRIM24TRIM33 | |
| SCHEMBL27257007 | 0.79 | SOS2 (0.42) | SOS2BRPF1NR4A2TRIM24TRIM33 | |
| SCHEMBL195995 | 0.78 | GPR84 (0.53) | POLBHTR2AMAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12024731-B2 | Methods and enzyme catalysts for the synthesis of non-canonical amino acids | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2024-07-02 | — | — | US | disclosed |
| US-12024731-B2 | Methods and enzyme catalysts for the synthesis of non-canonical amino acids | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2024-07-02 | — | — | US | disclosed |
| US-20200340024-A1 | METHODS AND ENZYME CATALYSTS FOR THE SYNTHESIS OF NON-CANONICAL AMINO ACIDS | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2020-10-29 | — | — | US | disclosed |
| US-10612056-B2 | Beta-substituted non-canonical amino acids | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2020-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12024731-B2 | Methods and enzyme catalysts for the synthesis of non-canonical amino acids | AANAT, AADAT, TPH1 | SOS2 3079/4885BRPF1 4544/4885NR4A2 4680/4885 |
| US-20200340024-A1 | METHODS AND ENZYME CATALYSTS FOR THE SYNTHESIS OF NON-CANONICAL AMINO ACIDS | AANAT, AADAT, TPH1 | SOS2 3079/4885BRPF1 4544/4885NR4A2 4680/4885 |
| US-10612056-B2 | Beta-substituted non-canonical amino acids | AANAT, TPH1, AADAT | SOS2 1894/4885BRPF1 4524/4885NR4A2 4191/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.