Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.36 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.36 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.36 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.36 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.36 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.36 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.36 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21803785 | 0.85 | GABRP (0.46) | KMT2AMEN1TOP2AHTR6KDM4E | |
| SCHEMBL24138085 | 0.84 | GABRP (0.43) | BCHEACHEKMT2AMEN1TP53 | |
| SCHEMBL21881961 | 0.84 | TP53 (0.34) | BCHEACHEKMT2AMEN1NR1I2 | |
| SCHEMBL21881935 | 0.78 | ALKBH5 (0.48) | KMT2AMEN1SLC5A2LMNACYP3A4 | |
| SCHEMBL21803727 | 0.76 | MEN1 (0.42) | BCHEACHEKMT2AMEN1NR1I2 | |
| SCHEMBL21881944 | 0.75 | BCHE (0.43) | BCHEACHEKMT2AMEN1TOP2A | |
| SCHEMBL21881938 | 0.75 | GABRP (0.43) | LMNATOP2AKDM4EALDH1A1MAPT | |
| SCHEMBL21803749 | 0.73 | CYP11B1 (0.49) | BCHEACHEKMT2AMEN1TP53 | |
| SCHEMBL21881941 | 0.73 | KMT2A (0.46) | KMT2AMEN1FGFR1TP53POLB | |
| SCHEMBL21803784 | 0.72 | CYP11B2 (0.40) | KMT2ALMNATOP2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210403470-A1 | NOVEL METHODS FOR PREPARATION OF SUBSTITUTED PYRIDINES AND RELATED NOVEL COMPOUNDS | WATKINS EDMOND BLAKE (US) | 2021-12-30 | — | — | US | disclosed |
| US-11117893-B2 | Methods for preparation of substituted pyridines and related novel compounds | UNION UNIVERSITY (US) | 2021-09-14 | — | — | US | disclosed |
| US-20200095245-A1 | NOVEL METHODS FOR PREPARATION OF SUBSTITUTED PYRIDINES AND RELATED NOVEL COMPOUNDS | UNION UNIVERSITY | 2020-03-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210403470-A1 | NOVEL METHODS FOR PREPARATION OF SUBSTITUTED PYRIDINES AND RELATED NOVEL COMPOUNDS | WEE1, WEE2, THEM6 | BCHE 2560/4885ACHE 931/4885KMT2A 2316/4885 |
| US-11117893-B2 | Methods for preparation of substituted pyridines and related novel compounds | NNMT, CYP4F3, AGPS | BCHE 2622/4885ACHE 939/4885KMT2A 2314/4885 |
| US-20200095245-A1 | NOVEL METHODS FOR PREPARATION OF SUBSTITUTED PYRIDINES AND RELATED NOVEL COMPOUNDS | WEE1, WEE2, THEM6 | BCHE 2560/4885ACHE 931/4885KMT2A 2316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.