Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | TOP2A | P11388 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | TNF | P01375 | 1/20 | 0.31 |
| ▸ | GABRP | O00591 | 1/20 | 0.31 |
| ▸ | GABRD | O14764 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21881937 | 0.84 | BCHE (0.43) | TP53BCHEACHETOP2APOLB | |
| SCHEMBL21803785 | 0.79 | GABRP (0.46) | TOP2AKMT2AGABRPGABRDGABRA1 | |
| SCHEMBL24138085 | 0.78 | GABRP (0.43) | TP53BCHEACHETOP2APOLB | |
| SCHEMBL21881938 | 0.76 | GABRP (0.43) | TOP2ALMNAGABRPGABRDGABRA1 | |
| SCHEMBL21881929 | 0.75 | KDM4E (0.47) | — | |
| SCHEMBL13141876 | 0.70 | KDM4E (0.47) | POLBKMT2ALMNATNFMEN1 | |
| SCHEMBL21881935 | 0.70 | ALKBH5 (0.48) | KMT2ALMNASLC5A2GABRPGABRD | |
| SCHEMBL21881944 | 0.70 | BCHE (0.43) | BCHEACHETOP2AKMT2AGABRP | |
| SCHEMBL21803752 | 0.69 | LMNA (0.44) | TOP2AKMT2ALMNAGABRPGABRD | |
| SCHEMBL21803749 | 0.68 | CYP11B1 (0.49) | TP53BCHEACHEKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11117893-B2 | Methods for preparation of substituted pyridines and related novel compounds | UNION UNIVERSITY (US) | 2021-09-14 | — | — | US | disclosed |
| US-20200095245-A1 | NOVEL METHODS FOR PREPARATION OF SUBSTITUTED PYRIDINES AND RELATED NOVEL COMPOUNDS | UNION UNIVERSITY | 2020-03-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11117893-B2 | Methods for preparation of substituted pyridines and related novel compounds | NNMT, CYP4F3, AGPS | TP53 1801/4885THRB 4835/4885BCHE 2622/4885 |
| US-20200095245-A1 | NOVEL METHODS FOR PREPARATION OF SUBSTITUTED PYRIDINES AND RELATED NOVEL COMPOUNDS | WEE1, WEE2, THEM6 | TP53 1913/4885THRB 4769/4885BCHE 2560/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.