Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | GPR3 | P46089 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25992599 | 0.93 | MEN1 (0.46) | MAPTHPGDLMNAALOX15TSHR | |
| SCHEMBL23037539 | 0.92 | NCF1 (0.43) | MAPTHPGDLMNAALOX15TSHR | |
| SCHEMBL23037565 | 0.90 | PABPC1 (0.43) | MAPTHPGDLMNAALOX15TSHR | |
| SCHEMBL23037532 | 0.87 | MAPT (0.48) | MAPTHPGDLMNATSHRCYP1A2 | |
| SCHEMBL23037533 | 0.87 | NPC1 (0.36) | MAPTHPGDLMNAALOX15TSHR | |
| SCHEMBL23037505 | 0.86 | MAPT (0.48) | MAPTHPGDLMNAALOX15TSHR | |
| SCHEMBL23037556 | 0.86 | MAPT (0.55) | MAPTLMNAALDH1A1HTTMEN1 | |
| SCHEMBL23037544 | 0.85 | CYP19A1 (0.47) | MAPTHPGDLMNAALOX15KDM4E | |
| SCHEMBL30060724 | 0.85 | CYP19A1 (0.47) | MAPTHPGDLMNAALOX15KDM4E | |
| SCHEMBL21883076 | 0.84 | TUBB4A (0.48) | MAPTHPGDLMNAALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12371417-B2 | Compounds with tubulin polymerisation inhibitory activity and immunomodulatory properties | Universite Paris-Saclay (FR) | 2025-07-29 | — | — | US | disclosed |
| US-20230203005-A1 | COMPOUNDS WITH TUBULIN POLYMERISATION INHIBITORY ACTIVITY AND IMMUNOMODULATORY PROPERTIES | Universite Paris-Saclay (FR) | 2023-06-29 | — | — | US | disclosed |
| US-20230203005-A1 | COMPOUNDS WITH TUBULIN POLYMERISATION INHIBITORY ACTIVITY AND IMMUNOMODULATORY PROPERTIES | Universite Paris-Saclay (FR) | 2023-06-29 | — | — | US | disclosed |
| US-20230203005-A1 | COMPOUNDS WITH TUBULIN POLYMERISATION INHIBITORY ACTIVITY AND IMMUNOMODULATORY PROPERTIES | Universite Paris-Saclay (FR) | 2023-06-29 | — | — | US | disclosed |
| EP-3853208-B1 | DRUG CONJUGATE COMPRISING QUINOLINE DERIVATIVES | CENTRE NAT RECH SCIENT (FR) | 2023-06-07 | — | — | EP | disclosed |
| US-11634405-B2 | Compounds with tubulin polymerisation inhibitory activity and immunomodulatory properties | UNIVERSITE PARIS-SACLAY PARC TECHNOLOGIQUE (FR) | 2023-04-25 | — | — | US | disclosed |
| US-11634405-B2 | Compounds with tubulin polymerisation inhibitory activity and immunomodulatory properties | UNIVERSITE PARIS-SACLAY PARC TECHNOLOGIQUE (FR) | 2023-04-25 | — | — | US | disclosed |
| US-20220023435-A1 | DRUG CONJUGATE COMPRISING QUINOLINE DERIVATIVES | Universite Paris-Saclay (FR) | 2022-01-27 | — | — | US | disclosed |
| US-20210230140-A1 | COMPOUNDS WITH TUBULIN POLYMERISATION INHIBITORY ACTIVITY AND IMMUNOMODULATORY PROPERTIES | Universite Paris-Saclay (FR) | 2021-07-29 | — | — | US | disclosed |
| US-20210230140-A1 | COMPOUNDS WITH TUBULIN POLYMERISATION INHIBITORY ACTIVITY AND IMMUNOMODULATORY PROPERTIES | Universite Paris-Saclay (FR) | 2021-07-29 | — | — | US | disclosed |
| EP-3784662-A1 | COMPOUNDS HAVING A TUBULIN-POLYMERISATION-INHIBITING ACTIVITY AND IMMUNOMODULATORY PROPERTIES | Université Paris-Saclay (FR) | 2021-03-03 | — | — | EP | disclosed |
| WO-2020058290-A1 | DRUG CONJUGATE COMPRISING QUINOLINE DERIVATIVES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2020-03-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12371417-B2 | Compounds with tubulin polymerisation inhibitory activity and immunomodulatory properties | TUBB1, TUBB, TUBB3 | MAPT 34/4885HPGD 2890/4885LMNA 3653/4885 |
| US-11634405-B2 | Compounds with tubulin polymerisation inhibitory activity and immunomodulatory properties | TUBB1, TUBB, TUBB3 | MAPT 34/4885HPGD 2890/4885LMNA 3653/4885 |
| US-20230203005-A1 | COMPOUNDS WITH TUBULIN POLYMERISATION INHIBITORY ACTIVITY AND IMMUNOMODULATORY PROPERTIES | TUBB1, TUBB, TUBB3 | MAPT 34/4885HPGD 2890/4885LMNA 3653/4885 |
| US-20220023435-A1 | DRUG CONJUGATE COMPRISING QUINOLINE DERIVATIVES | HRH3, ABCC3, ORC3 | MAPT 2856/4885HPGD 1779/4885LMNA 2506/4885 |
| US-20210230140-A1 | COMPOUNDS WITH TUBULIN POLYMERISATION INHIBITORY ACTIVITY AND IMMUNOMODULATORY PROPERTIES | TUBB1, TUBB, TUBB3 | MAPT 34/4885HPGD 2890/4885LMNA 3653/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.