Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 1/20 | 0.48 |
| ▸ | TUBB | P07437 | 1/20 | 0.48 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.48 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.48 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.48 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.48 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.48 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.48 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.48 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.48 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.48 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.48 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30060707 | 1.00 | TUBB4A (0.48) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL21883075 | 0.84 | MAPT (0.43) | MAPTHPGDLMNATSHRALOX15 | |
| SCHEMBL23037505 | 0.83 | MAPT (0.48) | MAPTHPGDLMNATSHRALOX15 | |
| SCHEMBL23037573 | 0.83 | TUBB4A (0.47) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL30062700 | 0.81 | KIF11 (0.41) | MAPTHPGDLMNATSHRALOX15 | |
| SCHEMBL23668707 | 0.81 | KIF11 (0.41) | MAPTHPGDLMNATSHRALOX15 | |
| SCHEMBL23668713 | 0.78 | CHKA (0.46) | MAPTHPGDLMNATSHRALOX15 | |
| SCHEMBL30060686 | 0.78 | CHKA (0.46) | MAPTHPGDLMNATSHRALOX15 | |
| SCHEMBL25992599 | 0.78 | MEN1 (0.46) | MAPTHPGDLMNATSHRALOX15 | |
| SCHEMBL23037539 | 0.77 | NCF1 (0.43) | MAPTHPGDLMNATSHRALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12371417-B2 | Compounds with tubulin polymerisation inhibitory activity and immunomodulatory properties | Universite Paris-Saclay (FR) | 2025-07-29 | — | — | US | disclosed |
| US-20230203005-A1 | COMPOUNDS WITH TUBULIN POLYMERISATION INHIBITORY ACTIVITY AND IMMUNOMODULATORY PROPERTIES | Universite Paris-Saclay (FR) | 2023-06-29 | — | — | US | disclosed |
| US-20230203005-A1 | COMPOUNDS WITH TUBULIN POLYMERISATION INHIBITORY ACTIVITY AND IMMUNOMODULATORY PROPERTIES | Universite Paris-Saclay (FR) | 2023-06-29 | — | — | US | disclosed |
| US-20230203005-A1 | COMPOUNDS WITH TUBULIN POLYMERISATION INHIBITORY ACTIVITY AND IMMUNOMODULATORY PROPERTIES | Universite Paris-Saclay (FR) | 2023-06-29 | — | — | US | disclosed |
| EP-3853208-B1 | DRUG CONJUGATE COMPRISING QUINOLINE DERIVATIVES | CENTRE NAT RECH SCIENT (FR) | 2023-06-07 | — | — | EP | disclosed |
| US-11634405-B2 | Compounds with tubulin polymerisation inhibitory activity and immunomodulatory properties | UNIVERSITE PARIS-SACLAY PARC TECHNOLOGIQUE (FR) | 2023-04-25 | — | — | US | disclosed |
| US-11634405-B2 | Compounds with tubulin polymerisation inhibitory activity and immunomodulatory properties | UNIVERSITE PARIS-SACLAY PARC TECHNOLOGIQUE (FR) | 2023-04-25 | — | — | US | disclosed |
| US-20220023435-A1 | DRUG CONJUGATE COMPRISING QUINOLINE DERIVATIVES | Universite Paris-Saclay (FR) | 2022-01-27 | — | — | US | disclosed |
| US-20210230140-A1 | COMPOUNDS WITH TUBULIN POLYMERISATION INHIBITORY ACTIVITY AND IMMUNOMODULATORY PROPERTIES | Universite Paris-Saclay (FR) | 2021-07-29 | — | — | US | disclosed |
| US-20210230140-A1 | COMPOUNDS WITH TUBULIN POLYMERISATION INHIBITORY ACTIVITY AND IMMUNOMODULATORY PROPERTIES | Universite Paris-Saclay (FR) | 2021-07-29 | — | — | US | disclosed |
| EP-3784662-A1 | COMPOUNDS HAVING A TUBULIN-POLYMERISATION-INHIBITING ACTIVITY AND IMMUNOMODULATORY PROPERTIES | Université Paris-Saclay (FR) | 2021-03-03 | — | — | EP | disclosed |
| WO-2020058290-A1 | DRUG CONJUGATE COMPRISING QUINOLINE DERIVATIVES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2020-03-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12371417-B2 | Compounds with tubulin polymerisation inhibitory activity and immunomodulatory properties | TUBB1, TUBB, TUBB3 | TUBB4A 10/4885TUBB 2/4885TUBA3C 15/4885 |
| US-11634405-B2 | Compounds with tubulin polymerisation inhibitory activity and immunomodulatory properties | TUBB1, TUBB, TUBB3 | TUBB4A 10/4885TUBB 2/4885TUBA3C 15/4885 |
| US-20230203005-A1 | COMPOUNDS WITH TUBULIN POLYMERISATION INHIBITORY ACTIVITY AND IMMUNOMODULATORY PROPERTIES | TUBB1, TUBB, TUBB3 | TUBB4A 10/4885TUBB 2/4885TUBA3C 15/4885 |
| US-20220023435-A1 | DRUG CONJUGATE COMPRISING QUINOLINE DERIVATIVES | HRH3, ABCC3, ORC3 | TUBB4A 1383/4885TUBB 739/4885TUBA3C 147/4885 |
| US-20210230140-A1 | COMPOUNDS WITH TUBULIN POLYMERISATION INHIBITORY ACTIVITY AND IMMUNOMODULATORY PROPERTIES | TUBB1, TUBB, TUBB3 | TUBB4A 10/4885TUBB 2/4885TUBA3C 15/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.