SCHEMBL21883889

SCHEMBL21883889

COc1cccc(Nc2c(C(C)C)cccc2C(C)C)c1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.63
KMT2A Q03164 5/20 0.63
POLB P06746 1/20 0.63
RAPGEF4 Q8WZA2 1/20 0.59
MAPT P10636 1/20 0.54
MAPK1 P28482 1/20 0.54
KCNH3 Q9ULD8 1/20 0.52
MTNR1B P49286 2/20 0.51
TSHR P16473 3/20 0.49
GFER P55789 1/20 0.49
IDO1 P14902 1/20 0.49
CYP1A2 P05177 1/20 0.49
CYP3A4 P08684 1/20 0.49
CYP2C9 P11712 1/20 0.49
CYP2C19 P33261 1/20 0.49
RECQL P46063 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
MTNR1A P48039 1/20 0.48
LMNA P02545 1/20 0.47
GAA P10253 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3628547 0.84 KMT2A (0.53) MEN1KMT2APOLBRAPGEF4MAPT
SCHEMBL12071030 0.83 ALDH1A1 (0.61) MEN1KMT2APOLBMAPTMAPK1
SCHEMBL1085867 0.80 MEN1 (0.71) MEN1KMT2APOLBRAPGEF4MAPT
SCHEMBL13302353 0.78 MEN1 (0.69) MEN1KMT2APOLBRAPGEF4MAPT
SCHEMBL5025966 0.76 LMNA (0.50) MEN1KMT2AMAPTMAPK1KCNH3
SCHEMBL1921496 0.76 MTNR1B (0.72) MEN1KMT2APOLBRAPGEF4MAPT
SCHEMBL22140743 0.76 MEN1 (0.67) MEN1KMT2APOLBRAPGEF4MAPT
SCHEMBL22864103 0.76 MEN1 (0.67) MEN1KMT2APOLBRAPGEF4MAPT
SCHEMBL16497593 0.76 RAPGEF4 (0.57) MEN1KMT2APOLBRAPGEF4MAPT
SCHEMBL27998900 0.76 KMT2A (0.46) MEN1KMT2APOLBRAPGEF4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020071798-A1 COMPOUND, COLORED RESIN COMPOSITION, COLOR FILTER, AND DISPLAY DEVICE 동우 화인켐 주식회사 2020-04-09 WO disclosed