SCHEMBL3628547

SCHEMBL3628547

CC(C)c1cccc(C(C)C)c1Nc1cccc(Nc2c(C(C)C)cccc2C(C)C)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.53
MEN1 O00255 3/20 0.53
CYP3A4 P08684 3/20 0.53
ALDH1A1 P00352 2/20 0.53
MAPT P10636 2/20 0.53
CYP1A2 P05177 2/20 0.53
USP2 O75604 1/20 0.53
APP P05067 1/20 0.53
HSP90AA1 P07900 1/20 0.53
HSP90AB1 P08238 1/20 0.53
CYP2D6 P10635 1/20 0.53
CYP2C9 P11712 1/20 0.53
ALOX15 P16050 1/20 0.53
ALOX12 P18054 1/20 0.53
MAPK1 P28482 1/20 0.53
CYP2C19 P33261 1/20 0.53
SNCA P37840 1/20 0.53
HSD17B10 Q99714 1/20 0.53
AR P10275 1/20 0.44
LMNA P02545 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5025966 0.87 LMNA (0.50) KMT2AMEN1CYP3A4ALDH1A1MAPT
SCHEMBL27998900 0.87 KMT2A (0.46) KMT2AMEN1CYP3A4ALDH1A1MAPT
SCHEMBL16497593 0.87 RAPGEF4 (0.57) KMT2AMEN1CYP3A4ALDH1A1MAPT
SCHEMBL2378671 0.86 HDAC6 (0.47) KMT2AMEN1CYP3A4ALDH1A1MAPT
SCHEMBL21883890 0.84 RAPGEF4 (0.59) KMT2AMEN1CYP3A4ALDH1A1MAPT
SCHEMBL21883889 0.84 MEN1 (0.63) KMT2AMEN1CYP3A4MAPTCYP1A2
SCHEMBL812723 0.84 GABRA1 (0.52) KMT2AMEN1CYP3A4ALDH1A1MAPT
SCHEMBL4808803 0.79 RAPGEF4 (0.48) KMT2AMEN1CYP3A4ALDH1A1MAPT
SCHEMBL9385483 0.79 KMT2A (0.42) KMT2AMEN1CYP3A4ALDH1A1MAPT
SCHEMBL2545467 0.78 KCNH3 (0.42) KMT2AMEN1CYP3A4ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2142496-B1 LUBRICATING COMPOSITIONS CONTAINING ASHLESS CATALYTIC ANTIOXIDANT ADDITIVES EXXONMOBIL RES & ENG CO (US) 2013-04-17 EP claimed
EP-2142496-A1 LUBRICATING COMPOSITIONS CONTAINING ASHLESS CATALYTIC ANTIOXIDANT ADDITIVES ExxonMobil Research and Engineering Company (US) 2010-01-13 EP claimed
US-20080248984-A1 Lubricating compositions containing ashless catalytic antioxidant additives EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2008-10-09 US claimed
WO-2008121304-A1 LUBRICATING COMPOSITIONS CONTAINING ASHLESS CATALYTIC ANTIOXIDANT ADDITIVES EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2008-10-09 WO claimed
EP-2142496-B1 LUBRICATING COMPOSITIONS CONTAINING ASHLESS CATALYTIC ANTIOXIDANT ADDITIVES EXXONMOBIL RES & ENG CO (US) 2013-04-17 EP disclosed
US-8080601-B2 Lubricating compositions containing ashless catalytic antioxidant additives EXXOMMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2011-12-20 US disclosed
EP-2142496-A1 LUBRICATING COMPOSITIONS CONTAINING ASHLESS CATALYTIC ANTIOXIDANT ADDITIVES ExxonMobil Research and Engineering Company (US) 2010-01-13 EP disclosed
US-20080248984-A1 Lubricating compositions containing ashless catalytic antioxidant additives EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2008-10-09 US disclosed
WO-2008121304-A1 LUBRICATING COMPOSITIONS CONTAINING ASHLESS CATALYTIC ANTIOXIDANT ADDITIVES EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2008-10-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080248984-A1 Lubricating compositions containing ashless catalytic antioxidant additives GPX1, SOD1, CAT KMT2A 1881/4885MEN1 3405/4885CYP3A4 2453/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.