SCHEMBL5025966

SCHEMBL5025966

CC(C)c1cccc(C(C)C)c1Nc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.50
KMT2A Q03164 3/20 0.50
HSD17B10 Q99714 4/20 0.47
ALDH1A1 P00352 4/20 0.47
CYP3A4 P08684 4/20 0.47
TSHR P16473 4/20 0.47
ALOX15 P16050 3/20 0.47
ALOX12 P18054 3/20 0.47
TDP1 Q9NUW8 3/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
THRB P10828 1/20 0.47
RECQL P46063 1/20 0.47
ATM Q13315 1/20 0.47
KDM1A O60341 1/20 0.46
MEN1 O00255 2/20 0.44
MAPT P10636 2/20 0.44
MAPK1 P28482 2/20 0.44
CYP1A2 P05177 2/20 0.44
USP2 O75604 1/20 0.44
APP P05067 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2378671 0.91 HDAC6 (0.47) LMNAKMT2AHSD17B10ALDH1A1CYP3A4
SCHEMBL3628547 0.87 KMT2A (0.53) LMNAKMT2AHSD17B10ALDH1A1CYP3A4
SCHEMBL812723 0.84 GABRA1 (0.52) LMNAKMT2AHSD17B10ALDH1A1CYP3A4
SCHEMBL4808803 0.83 RAPGEF4 (0.48) LMNAKMT2AHSD17B10ALDH1A1CYP3A4
SCHEMBL2545467 0.82 KCNH3 (0.42) LMNAKMT2AHSD17B10ALDH1A1CYP3A4
SCHEMBL6744857 0.80 LMNA (0.47) LMNAKMT2ACYP3A4TSHRL3MBTL1
SCHEMBL31447156 0.80 LMNA (0.47) LMNAKMT2ACYP3A4TSHRL3MBTL1
SCHEMBL16583962 0.80 HDAC6 (0.53) LMNAKMT2AALDH1A1TDP1L3MBTL1
SCHEMBL28655825 0.80 PLK1 (0.40) LMNAKMT2AHSD17B10ALDH1A1CYP3A4
SCHEMBL12071030 0.79 ALDH1A1 (0.61) LMNAKMT2AHSD17B10ALDH1A1ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10797259-B2 Organic light-emitting diode with high efficiency SFC CO., LTD. (KR) 2020-10-06 US disclosed
US-20180019430-A1 Organic light-emitting diode with high efficiency SFC CO., LTD. (KR) 2018-01-18 US disclosed
US-20180019430-A1 Organic light-emitting diode with high efficiency SFC CO., LTD. (KR) 2018-01-18 US disclosed
EP-3269790-A1 ORGANIC LIGHT-EMITTING DIODE WITH HIGH EFFICIENCY SFC Co., Ltd. (KR) 2018-01-17 EP disclosed
US-20080070308-A1 Portous Article For Delivering Chemical Substances LIFECYCLE PHARMA A/S (DK) 2008-03-20 US disclosed
US-20080070308-A1 Portous Article For Delivering Chemical Substances LIFECYCLE PHARMA A/S (DK) 2008-03-20 US disclosed
US-20080070308-A1 Portous Article For Delivering Chemical Substances LIFECYCLE PHARMA A/S (DK) 2008-03-20 US disclosed
CN-1976751-A Porous article for delivering chemical substances LUNDBECK & CO AS H (DK) 2007-06-06 CN disclosed
EP-1771243-A1 POROUS ARTICLE FOR DELIVERING CHEMICAL SUBSTANCES H.Lundbeck A/S (DK) 2007-04-11 EP disclosed
WO-2006000227-A1 POROUS ARTICLE FOR DELIVERING CHEMICAL SUBSTANCES H. LUNDBECK A/S (DK) 2006-01-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180019430-A1 Organic light-emitting diode with high efficiency CYBA, CYP1A1, CYP1B1 LMNA 524/4885KMT2A 1317/4885HSD17B10 487/4885
US-10797259-B2 Organic light-emitting diode with high efficiency CYBA, CYP1A1, CYP1B1 LMNA 524/4885KMT2A 1317/4885HSD17B10 487/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.