Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 3/20 | 0.54 |
| ▸ | JAK3 | P52333 | 3/20 | 0.54 |
| ▸ | JAK1 | P23458 | 2/20 | 0.54 |
| ▸ | PGR | P06401 | 10/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | HRH2 | P25021 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3565009 | 0.80 | CTSL (0.40) | JAK2JAK3JAK1PGRMCHR1 | |
| SCHEMBL21824810 | 0.79 | JAK2 (0.47) | JAK2JAK3JAK1MCHR1KDM1A | |
| SCHEMBL148917 | 0.76 | MAOA (0.46) | JAK2JAK3JAK1PGRHRH3 | |
| SCHEMBL28823769 | 0.74 | SLC6A2 (0.50) | JAK2JAK3JAK1KDM1A | |
| SCHEMBL3572453 | 0.74 | ALDH1A1 (0.49) | JAK2JAK3JAK1 | |
| SCHEMBL24118018 | 0.73 | GPR119 (0.60) | JAK2JAK3JAK1 | |
| SCHEMBL3033753 | 0.73 | PGR (0.71) | PGR | |
| SCHEMBL21824804 | 0.73 | GPR119 (0.60) | JAK2JAK3JAK1 | |
| Hydrochloric Acid SCHEMBL23302664 | 0.73 | SLC6A2 (0.49) | JAK2JAK3JAK1KDM1A | |
| SCHEMBL2056297 | 0.73 | FPR2 (0.51) | PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020070610-A1 | NOVEL OXADIAZOLES | PI INDUSTRIES LTD. (IN) | 2020-04-09 | — | — | WO | disclosed |