Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | PNMT | P11086 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2453350 | 0.73 | LMNA (0.69) | LMNACHRM2ADORA3KCNH2BCHE | |
| SCHEMBL29373003 | 0.73 | LMNA (0.69) | LMNACHRM2ADORA3KCNH2BCHE | |
| SCHEMBL5582092 | 0.70 | LMNA (0.51) | LMNAPGRCHRM2ADORA3KCNH2 | |
| SCHEMBL29757969 | 0.70 | NPC1 (0.50) | PNMTPGRCA1CA2CA4 | |
| SCHEMBL29170221 | 0.70 | CHEK1 (0.40) | LMNAPNMTNPC1RAB9AHTR7 | |
| SCHEMBL5581522 | 0.69 | LMNA (0.50) | LMNAPGRCHRM2ADORA3KCNH2 | |
| SCHEMBL30103334 | 0.69 | PNMT (0.63) | LMNAPNMTPGRCA1CA2 | |
| SCHEMBL524602 | 0.69 | PNMT (0.63) | LMNAPNMTPGRCA1CA2 | |
| SCHEMBL22680481 | 0.69 | NPC1 (0.43) | LMNAPNMTPGRNPC1RAB9A | |
| SCHEMBL30631774 | 0.68 | PGR (0.49) | LMNAPNMTPGRCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020056859-A1 | 9,10-DIHYDROACRIDINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | 宁波卢米蓝新材料有限公司 | 2020-03-26 | — | — | WO | disclosed |