Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | GRIA1 | P42261 | 5/20 | 0.35 |
| ▸ | DRD2 | P14416 | 3/20 | 0.35 |
| ▸ | CACNG8 | Q8WXS5 | 2/20 | 0.34 |
| ▸ | TACR3 | P29371 | 2/20 | 0.34 |
| ▸ | CPT2 | P23786 | 1/20 | 0.34 |
| ▸ | CPT1A | P50416 | 1/20 | 0.34 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 2/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.33 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18190562 | 0.82 | CXCR3 (0.43) | GRIA1DRD2CACNG8TACR3HTR7 | |
| SCHEMBL18202983 | 0.76 | SMARCA2 (0.48) | DRD2 | |
| SCHEMBL23536457 | 0.74 | GFER (0.34) | SLC6A7DRD2HTR7MEN1KMT2A | |
| SCHEMBL2760636 | 0.72 | DRD2 (0.51) | DRD2MEN1KMT2APOLBHTR1A | |
| SCHEMBL17491559 | 0.72 | ADRA2C (0.45) | SLC6A7MEN1KMT2APOLBMAPT | |
| SCHEMBL30881604 | 0.72 | ADRA2C (0.45) | SLC6A7MEN1KMT2APOLBMAPT | |
| SCHEMBL2327343 | 0.71 | RBP4 (0.37) | SLC6A7DRD2HTR7MEN1KMT2A | |
| SCHEMBL5357553 | 0.71 | MEN1 (0.35) | MEN1KMT2APOLBMAPTHTR1A | |
| SCHEMBL4558300 | 0.70 | SLC6A9 (0.44) | SLC6A7DRD2HTR7HTR1AHTR6 | |
| SCHEMBL29252729 | 0.70 | AGTR2 (0.48) | SLC6A7DRD2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3288936-B1 | BENZIMIDAZOLONE AND BENZOTHIAZOLONE COMPOUNDS AND THEIR USE AS AMPA RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-05-06 | — | — | EP | disclosed |