Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.80 |
| ▸ | MEN1 | O00255 | 8/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.80 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.70 |
| ▸ | LMNA | P02545 | 4/20 | 0.70 |
| ▸ | USP2 | O75604 | 3/20 | 0.70 |
| ▸ | HTT | P42858 | 3/20 | 0.70 |
| ▸ | RORC | P51449 | 3/20 | 0.69 |
| ▸ | GAA | P10253 | 1/20 | 0.66 |
| ▸ | PKM | P14618 | 1/20 | 0.66 |
| ▸ | CNR1 | P21554 | 1/20 | 0.64 |
| ▸ | CNR2 | P34972 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 4/20 | 0.63 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.63 |
| ▸ | RORA | P35398 | 1/20 | 0.63 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.63 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.63 |
| ▸ | RORB | Q92753 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10187026 | 1.00 | MAPT (0.80) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL13454756 | 0.90 | MEN1 (0.66) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL27180835 | 0.88 | MAPT (0.81) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL2692159 | 0.84 | KMT2A (1.00) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4012337 | 0.84 | MAPT (0.74) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL27180628 | 0.83 | NR2F2 (0.79) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL10187017 | 0.83 | NR3C1 (0.81) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL1494935 | 0.81 | RORC (0.72) | MAPTKMT2AMEN1SMN1; SMN2RORC | |
| SCHEMBL13454767 | 0.81 | KMT2A (0.67) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL29978195 | 0.81 | L3MBTL1 (0.70) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11834446-B2 | Methods and compositions useful in treating cancer and reducing Wnt mediated effects in a cell | STEMSYNERGY THERAPEUTICS, INC. (US) | 2023-12-05 | — | — | US | disclosed |
| US-20230110928-A1 | METHODS AND COMPOSITIONS USEFUL IN TREATING CANCER AND REDUCING WNT MEDIATED EFFECTS IN A CELL | STEMSYNERGY THERAPEUTICS, INC. | 2023-04-13 | — | — | US | disclosed |
| US-11512081-B2 | Methods and compositions useful in treating cancer and reducing WNT mediated effects in a cell | STEMSYNERGY THERAPEUTICS, INC. (US) | 2022-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11834446-B2 | Methods and compositions useful in treating cancer and reducing Wnt mediated effects in a cell | WNT3A, WNT1, WNT3 | MAPT 3825/4885KMT2A 3839/4885MEN1 4226/4885 |
| US-20230110928-A1 | METHODS AND COMPOSITIONS USEFUL IN TREATING CANCER AND REDUCING WNT MEDIATED EFFECTS IN A CELL | WNT3A, WNT1, WNT3 | MAPT 3825/4885KMT2A 3839/4885MEN1 4226/4885 |
| US-11512081-B2 | Methods and compositions useful in treating cancer and reducing WNT mediated effects in a cell | WNT3A, WNT1, WNT3 | MAPT 3825/4885KMT2A 3839/4885MEN1 4226/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.