Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.33 |
| ▸ | AURKA | O14965 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.30 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.30 |
| ▸ | PRKACA | P17612 | 1/20 | 0.30 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | MARK3 | P27448 | 1/20 | 0.30 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.30 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.30 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
| ▸ | MARK2 | Q7KZI7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5559244 | 0.77 | NUDT1 (0.44) | NUDT1LMNACHEK1AURKALRRK2 | |
| SCHEMBL18312090 | 0.70 | NUDT1 (0.39) | NUDT1LRRK2 | |
| SCHEMBL23079428 | 0.68 | LMNA (0.33) | NUDT1LMNACHEK1AURKAHTT | |
| SCHEMBL2316376 | 0.67 | CHEK1 (0.42) | NUDT1LMNACHEK1AURKAPDPK1 | |
| SCHEMBL19864857 | 0.67 | LIMK1 (0.33) | NUDT1LMNAHTT | |
| SCHEMBL8856393 | 0.64 | CHEK1 (0.47) | NUDT1LMNACHEK1AURKAPDPK1 | |
| SCHEMBL9929454 | 0.62 | CHEK1 (0.35) | NUDT1CHEK1AURKAPDPK1CHEK2 | |
| SCHEMBL13701448 | 0.62 | CHEK1 (0.39) | NUDT1LMNACHEK1AURKAPDPK1 | |
| SCHEMBL9929453 | 0.62 | CHEK1 (0.35) | NUDT1CHEK1AURKAPDPK1CHEK2 | |
| SCHEMBL25593925 | 0.62 | NOS3 (0.41) | NUDT1LMNACHEK1AURKAPDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3858833-A1 | AMINONORDECANE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Nanjing Transthera Biosciences Co., Ltd. (CN) | 2021-08-04 | — | — | EP | disclosed |
| WO-2020063012-A1 | AMINONORDECANE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 南京亘泰医药技术有限公司 | 2020-04-02 | — | — | WO | disclosed |