Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 7/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20161623 | 0.73 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2RXFP1MAPTMEN1 | |
| SCHEMBL21935436 | 0.70 | RAB9A (0.52) | ALDH1A1TP53HSD17B10SMN1; SMN2RXFP1 | |
| SCHEMBL4532619 | 0.63 | ALDH1A1 (0.41) | PDE4BALDH1A1MAPT | |
| SCHEMBL21133501 | 0.61 | TP53 (0.55) | ALDH1A1TP53HTTRXFP1MAPT | |
| SCHEMBL20161621 | 0.60 | NPC1 (0.42) | ALDH1A1TP53HTTSMN1; SMN2MAPT | |
| SCHEMBL10587862 | 0.59 | ALDH1A1 (0.38) | ALDH1A1MAPTADORA2B | |
| SCHEMBL16072279 | 0.58 | MAPT (0.55) | ALDH1A1SMN1; SMN2MAPTMEN1GAA | |
| SCHEMBL4524260 | 0.57 | — | — | |
| SCHEMBL20543330 | 0.56 | MAPT (0.72) | ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL21936463 | 0.55 | APP (0.39) | ALDH1A1TP53HSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2999699-B1 | PURINE DIONES AS WNT PATHWAY MODULATORS | AGENCY SCIENCE TECH & RES (SG) | 2020-04-29 | — | — | EP | disclosed |