Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.30 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.30 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21945094 | 0.89 | TLR8 (0.34) | ARTLR8 | |
| SCHEMBL21945696 | 0.89 | NPSR1 (0.35) | CYP2C9CYP2C19CYP1A2NPSR1L3MBTL1 | |
| SCHEMBL21945135 | 0.86 | ADORA2A (0.42) | CYP2C9CYP2C19CYP1A2NPSR1L3MBTL1 | |
| SCHEMBL21945093 | 0.83 | ADORA2A (0.41) | CYP2C9CYP2C19CYP1A2NPSR1L3MBTL1 | |
| SCHEMBL21945097 | 0.80 | PRMT5 (0.38) | ARCYP2C9CYP2C19CYP1A2NPSR1 | |
| SCHEMBL21945228 | 0.80 | EGFR (0.40) | CYP2C9CYP2C19CYP1A2NPSR1L3MBTL1 | |
| SCHEMBL18004307 | 0.79 | AR (0.46) | ARCYP2C9CYP2C19CYP1A2NPSR1 | |
| SCHEMBL21945193 | 0.77 | SLC6A2 (0.36) | ADORA2AKIF11 | |
| SCHEMBL21945754 | 0.76 | KIF11 (0.38) | ARCYP2C9CYP2C19CYP1A2NPSR1 | |
| SCHEMBL21945716 | 0.75 | PGR (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10626095-B2 | Cyanotriazole compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2020-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10626095-B2 | Cyanotriazole compounds | CS, PC, ACAT1 | AR 3449/4885CYP2C9 1517/4885CYP2C19 1954/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.